Literature DB >> 16023538

Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina.

Massimo Natale1, Pietro Spennato, Luciano Savarese, Antonio Bocchetti, Salvatore Esposito, Rosario Barbato.   

Abstract

Metastatic involvement of the cerebro-spinal fluid (CSF) pathway in oligodendrogliomas is not uncommon; however, symptomatic involvement of the spinal cord is very rare: less of 10 cases have been published. To our knowledge, an intracranial oligodendroglioma presenting with symptoms of drop metastases in the cauda equina has never been reported. We report a case of 67-year-old woman who after 1 month of severe low back and legs pain developed symptoms of raised intracranial pressure. A spinal cord MRI showed multiple intradural nodular lesions at the level of the cauda equina, a MRI of the brain showed an intraventricular brain tumor. The histopathological diagnosis of both surgically treated lesions was anaplastic oligodendroglioma. The choices adopted in planning diagnostic and therapeutical procedures are discussed. The importance of the clinical and neuroradiological data in the diagnosis is stressed. Pathophysiology of the seeding of intracranial tumours via the cerebrospinal fluid is reviewed.

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Year:  2005        PMID: 16023538     DOI: 10.1016/j.clineuro.2004.09.013

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  3 in total

1.  Symptomatic spinal cord metastasis from cerebral oligodendroglioma.

Authors:  A Elefante; C Peca; M L Del Basso De Caro; C Russo; F Formicola; G Mariniello; A Brunetti; F Maiuri
Journal:  Neurol Sci       Date:  2011-09-17       Impact factor: 3.307

2.  Clinical, radiological, pathological and prognostic aspects of intraventricular oligodendroglioma: comparison with central neurocytoma.

Authors:  Xiang Xiao; Jun Zhou; Jun Wang; Lei Yang; Chunhong Wang; Yikai Xu; Yuankui Wu
Journal:  J Neurooncol       Date:  2017-09-12       Impact factor: 4.130

3.  Brain gliomas presenting with symptoms of spinal cord metastasis.

Authors:  Giuseppe Mariniello; Carmela Peca; Marialaura Del Basso De Caro; Biagio Carotenuto; Fabiana Formicola; Andrea Elefante; Francesco Maiuri
Journal:  Neuroradiol J       Date:  2015-07-27
  3 in total

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