Literature DB >> 16023059

Ontologies and semantic data integration.

Stephen P Gardner1.   

Abstract

The increased generation of data in the pharmaceutical R&D process has failed to generate the expected returns in terms of enhanced productivity and pipelines. The inability of existing integration strategies to organize and apply the available knowledge to the range of real scientific and business issues is impacting on not only productivity but also transparency of information in crucial safety and regulatory applications. The new range of semantic technologies based on ontologies enables the proper integration of knowledge in a way that is reusable by several applications across businesses, from discovery to corporate affairs.

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Year:  2005        PMID: 16023059     DOI: 10.1016/S1359-6446(05)03504-X

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  13 in total

1.  Bio-Ontology and text: bridging the modeling gap.

Authors:  Carol Friedman; Tara Borlawsky; Lyudmila Shagina; H Rosie Xing; Yves A Lussier
Journal:  Bioinformatics       Date:  2006-07-26       Impact factor: 6.937

2.  LORD: a phenotype-genotype semantically integrated biomedical data tool to support rare disease diagnosis coding in health information systems.

Authors:  Remy Choquet; Meriem Maaroufi; Yannick Fonjallaz; Albane de Carrara; Pierre-Yves Vandenbussche; Ferdinand Dhombres; Paul Landais
Journal:  AMIA Annu Symp Proc       Date:  2015-11-05

Review 3.  Clinical translation of genotyping and haplotyping data: implementation of in vivo pharmacology experience leading drug prescription to pharmacotyping.

Authors:  Ioannis S Vizirianakis
Journal:  Clin Pharmacokinet       Date:  2007       Impact factor: 6.447

4.  The Cell Cycle Ontology: an application ontology for the representation and integrated analysis of the cell cycle process.

Authors:  Erick Antezana; Mikel Egaña; Ward Blondé; Aitzol Illarramendi; Iñaki Bilbao; Bernard De Baets; Robert Stevens; Vladimir Mironov; Martin Kuiper
Journal:  Genome Biol       Date:  2009-05-29       Impact factor: 13.583

5.  Clinical research informatics: a conceptual perspective.

Authors:  Michael G Kahn; Chunhua Weng
Journal:  J Am Med Inform Assoc       Date:  2012-04-20       Impact factor: 4.497

6.  The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery.

Authors:  Michel Dumontier; Christopher Jo Baker; Joachim Baran; Alison Callahan; Leonid Chepelev; José Cruz-Toledo; Nicholas R Del Rio; Geraint Duck; Laura I Furlong; Nichealla Keath; Dana Klassen; Jamie P. McCusker; Núria Queralt-Rosinach; Matthias Samwald; Natalia Villanueva-Rosales; Mark D Wilkinson; Robert Hoehndorf
Journal:  J Biomed Semantics       Date:  2014-03-06

7.  Toward a comprehensive drug ontology: extraction of drug-indication relations from diverse information sources.

Authors:  Mark E Sharp
Journal:  J Biomed Semantics       Date:  2017-01-10

8.  Ontologies for bioinformatics.

Authors:  Nadine Schuurman; Agnieszka Leszczynski
Journal:  Bioinform Biol Insights       Date:  2008-03-12

9.  Developing a data infrastructure for a learning health system: the PORTAL network.

Authors:  Elizabeth A McGlynn; Tracy A Lieu; Mary L Durham; Alan Bauck; Reesa Laws; Alan S Go; Jersey Chen; Heather Spencer Feigelson; Douglas A Corley; Deborah Rohm Young; Andrew F Nelson; Arthur J Davidson; Leo S Morales; Michael G Kahn
Journal:  J Am Med Inform Assoc       Date:  2014-05-12       Impact factor: 4.497

10.  PEDSnet: a National Pediatric Learning Health System.

Authors:  Christopher B Forrest; Peter A Margolis; L Charles Bailey; Keith Marsolo; Mark A Del Beccaro; Jonathan A Finkelstein; David E Milov; Veronica J Vieland; Bryan A Wolf; Feliciano B Yu; Michael G Kahn
Journal:  J Am Med Inform Assoc       Date:  2014-05-12       Impact factor: 4.497

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