Literature DB >> 16021276

Follow-up of children and adolescents with short stature: the importance of the growth rate.

Maria Wany Louzada Strufaldi1, Edina Mariko Koga da Silva, Rosana Fiorini Puccini.   

Abstract

CONTEXT AND
OBJECTIVE: Short stature is defined as a height of more than two standard deviations below the average for a given age and sex in a reference population. The objective was to describe follow-up conducted among short-stature children and adolescents. DESIGN AND
SETTING: Descriptive study, at the Growth outpatient clinic, Department of Pediatrics, Universidade Federal de São Paulo.
METHODS: The study included 152 patients aged 2 to 15 years who had height for age of less than P5, on the National Center for Health Statistics curve. The children underwent nutritional evaluation, and several variables relating to height and growth rate were calculated to establish etiological diagnosis. Bone age was evaluated by X-ray.
RESULTS: The majority (63.2%) were male. In 77.8%, the stature observed was within the family pattern. Among the 99 patients followed up for more than 6 months, 17.2% presented inadequate growth rates. The preponderant etiological diagnosis for short stature was familial/constitutional in 58.6% of the cases; 27 patients (34.2%) with adequate growth rate presented bone age alterations. Even with inadequate growth rates, 75% of such patients had a normal result from growth hormone stimulation testing. Close to 90% of patients with a diagnosis of short stature of familial/constitutional origin and intrauterine growth retardation presented adequate growth rate. The genetic etiology was significantly characteristic of patients with inadequate growth rate.
CONCLUSION: Growth rate assessment must form part of the investigation and follow-up of short-stature cases. However, its utilization and validity should form part of an overall view of each patient.

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Mesh:

Year:  2005        PMID: 16021276     DOI: 10.1590/s1516-31802005000300008

Source DB:  PubMed          Journal:  Sao Paulo Med J        ISSN: 1516-3180            Impact factor:   1.044


  2 in total

Review 1.  A Proposal for the Interpretation of Serum IGF-I Concentration as Part of Laboratory Screening in Children with Growth Failure

Authors:  Jan M. Wit; Martin Bidlingmaier; Christiaan de Bruin; Wilma Oostdijk
Journal:  J Clin Res Pediatr Endocrinol       Date:  2019-12-17

2.  Stature-weight growth delays: Clinical and etiological aspects.

Authors:  Houda Salhi; Asmae Lahlou; Mamadou L Dante; Hanan El Ouahabi; Saïd Boujraf; Farida Ajdi
Journal:  J Family Med Prim Care       Date:  2018 Sep-Oct
  2 in total

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