Literature DB >> 16020795

Update on estimation of mutation rates using data from fluctuation experiments.

Qi Zheng1.   

Abstract

This note discusses a minor mathematical error and a problematic mathematical assumption in Luria and Delbrück's (1943) classic article on fluctuation analysis. In addition to suggesting remedial measures, the note provides information on the latest development of techniques for estimating mutation rates using data from fluctuation experiments.

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Year:  2005        PMID: 16020795      PMCID: PMC1456792          DOI: 10.1534/genetics.104.035774

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  10 in total

1.  An explicit representation of the Luria-Delbrück distribution.

Authors:  W P Angerer
Journal:  J Math Biol       Date:  2001-02       Impact factor: 2.259

Review 2.  Progress of a half century in the study of the Luria-Delbrück distribution.

Authors:  Q Zheng
Journal:  Math Biosci       Date:  1999 Nov-Dec       Impact factor: 2.144

Review 3.  Determining mutation rates in bacterial populations.

Authors:  W A Rosche; P L Foster
Journal:  Methods       Date:  2000-01       Impact factor: 3.608

4.  Statistical and algorithmic methods for fluctuation analysis with SALVADOR as an implementation.

Authors:  Qi Zheng
Journal:  Math Biosci       Date:  2002-04       Impact factor: 2.144

5.  New algorithms for Luria-Delbrück fluctuation analysis.

Authors:  Qi Zheng
Journal:  Math Biosci       Date:  2005-08       Impact factor: 2.144

6.  Mutations of Bacteria from Virus Sensitivity to Virus Resistance.

Authors:  S E Luria; M Delbrück
Journal:  Genetics       Date:  1943-11       Impact factor: 4.562

7.  Fluctuation analysis: the probability distribution of the number of mutants under different conditions.

Authors:  F M Stewart; D M Gordon; B R Levin
Journal:  Genetics       Date:  1990-01       Impact factor: 4.562

8.  The distribution of the numbers of mutants in bacterial populations.

Authors:  D E LEA; C A COULSON
Journal:  J Genet       Date:  1949-12       Impact factor: 1.166

9.  A theoretical study on spontaneous mutation rate.

Authors:  S Kondo
Journal:  Mutat Res       Date:  1972-04       Impact factor: 2.433

10.  Luria-Delbrück fluctuation experiments: design and analysis.

Authors:  M E Jones; S M Thomas; A Rogers
Journal:  Genetics       Date:  1994-03       Impact factor: 4.562

  10 in total
  2 in total

1.  Clonal aspects of plant cell proliferation and their applications to animal cells and bacteria.

Authors:  R W Korn
Journal:  Cell Prolif       Date:  2008-04-23       Impact factor: 6.831

2.  Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis.

Authors:  John M Hinz; Peter B Nham; Salustra S Urbin; Irene M Jones; Larry H Thompson
Journal:  Nucleic Acids Res       Date:  2007-05-21       Impact factor: 16.971

  2 in total

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