Literature DB >> 16020777

Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation.

Xiaolin Bi1, Min Gong, Deepa Srikanta, Yikang S Rong.   

Abstract

Others have suggested recently that the conserved ATM checkpoint kinase is minimally involved in controlling the G(2)/M checkpoint in Drosophila that serves to prevent mitotic entry in the presence of DNA damage. Our data indicate that both ATM and its regulator Mre11 are important for the checkpoint and that their roles become essential when animals are challenged with a low dose of X rays or when they have compromised checkpoint function of the ATM-related ATR kinase.

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Year:  2005        PMID： 16020777      PMCID： PMC1456793          DOI： 10.1534/genetics.105.047720

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  18 in total

1.  mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development.

Authors:  M H Brodsky; J J Sekelsky; G Tsang; R S Hawley; G M Rubin
Journal:  Genes Dev       Date:  2000-03-15       Impact factor: 11.361

Review 2.  Cell cycle checkpoint signaling through the ATM and ATR kinases.

Authors:  R T Abraham
Journal:  Genes Dev       Date:  2001-09-01       Impact factor: 11.361

3.  An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication.

Authors:  Vincenzo Costanzo; David Shechter; Patrick J Lupardus; Karlene A Cimprich; Max Gottesman; Jean Gautier
Journal:  Mol Cell       Date:  2003-01       Impact factor: 17.970

4.  Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.

Authors:  Bo Xu; Seong-Tae Kim; Dae-Sik Lim; Michael B Kastan
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

Review 5.  The ATM gene and the radiobiology of ataxia-telangiectasia.

Authors:  T J Jorgensen; Y Shiloh
Journal:  Int J Radiat Biol       Date:  1996-05       Impact factor: 2.694

6.  Drosophila p53 preserves genomic stability by regulating cell death.

Authors:  Naoko Sogame; Misoo Kim; John M Abrams
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-02       Impact factor: 11.205

7.  Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

Authors:  Lee Zou; Stephen J Elledge
Journal:  Science       Date:  2003-06-06       Impact factor: 47.728

8.  The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development.

Authors:  Young-Han Song; Gladys Mirey; Martha Betson; Daniel A Haber; Jeffrey Settleman
Journal:  Curr Biol       Date:  2004-08-10       Impact factor: 10.834

9.  DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

Authors:  Oscar Fernandez-Capetillo; Hua-Tang Chen; Arkady Celeste; Irene Ward; Peter J Romanienko; Julio C Morales; Kazuhito Naka; Zhenfang Xia; R Daniel Camerini-Otero; Noboru Motoyama; Phillip B Carpenter; William M Bonner; Junjie Chen; André Nussenzweig
Journal:  Nat Cell Biol       Date:  2002-12       Impact factor: 28.824

10.  Chk2 activation dependence on Nbs1 after DNA damage.

Authors:  G Buscemi; C Savio; L Zannini; F Miccichè; D Masnada; M Nakanishi; H Tauchi; K Komatsu; S Mizutani; K Khanna; P Chen; P Concannon; L Chessa; D Delia
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272
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  22 in total

Review 1.  Telomere capping in Drosophila: dealing with chromosome ends that most resemble DNA breaks.

Authors:  Yikang S Rong
Journal:  Chromosoma       Date:  2008-01-10       Impact factor: 4.316

2.  Clustering and protein dynamics of Drosophila melanogaster telomeres.

Authors:  Natalia Wesolowska; Flavia L Amariei; Yikang S Rong
Journal:  Genetics       Date:  2013-07-26       Impact factor: 4.562

3.  Drosophila dCBP is involved in establishing the DNA replication checkpoint.

Authors:  Sarah Smolik; Kristen Jones
Journal:  Mol Cell Biol       Date:  2006-10-16       Impact factor: 4.272

4.  Drosophila ATR in double-strand break repair.

Authors:  Jeannine R LaRocque; Burnley Jaklevic; Tin Tin Su; Jeff Sekelsky
Journal:  Genetics       Date:  2006-12-28       Impact factor: 4.562

5.  E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.

Authors:  Ana Guarner; Robert Morris; Michael Korenjak; Myriam Boukhali; Maria Paula Zappia; Capucine Van Rechem; Johnathan R Whetstine; Sridhar Ramaswamy; Lee Zou; Maxim V Frolov; Wilhelm Haas; Nicholas J Dyson
Journal:  Dev Cell       Date:  2017-12-07       Impact factor: 12.270

6.  Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven.

Authors:  Sige Zou; Joy Chang; Leesa LaFever; Wangli Tang; Erika L Johnson; Jack Hu; Ronit Wilk; Henry M Krause; Daniela Drummond-Barbosa; Pablo M Irusta
Journal:  Cell Cycle       Date:  2011-03-15       Impact factor: 4.534

7.  Reducing DNA polymerase alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects.

Authors:  Jeannine R LaRocque; Diana L Dougherty; Sumreen K Hussain; Jeff Sekelsky
Journal:  Genetics       Date:  2007-05-04       Impact factor: 4.562

8.  DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function.

Authors:  Sushmita Mukherjee; Matthew C LaFave; Jeff Sekelsky
Journal:  DNA Repair (Amst)       Date:  2009-04-22

9.  Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia.

Authors:  Stacey A Rimkus; Rebeccah J Katzenberger; Anthony T Trinh; Gerald E Dodson; Randal S Tibbetts; David A Wassarman
Journal:  Genes Dev       Date:  2008-04-11       Impact factor: 11.361

10.  Loss of the histone variant H2A.Z restores capping to checkpoint-defective telomeres in Drosophila.

Authors:  Yikang S Rong
Journal:  Genetics       Date:  2008-10-09       Impact factor: 4.562
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