E Lee1, J Koo. 1. Indiana School of Medicine, Department of Dermatology, Regenstrief Health Center, Indianapolis, IN 46202, USA. ernlee@iupui.edu
Abstract
BACKGROUND: Compared with the original Goeckerman therapy devised by Dr Goeckerman in the 1930s, modern modified Goeckerman therapy in the second millennium shows significantly enhanced efficacy by improvements in technology (e.g. narrowband UVB) and the possibility of adding other relatively safe therapeutic options for more resistant cases to enhance efficacy without compromising the basic safety profile. METHODS: For approximately 6 months, psoriasis patients undergoing Goeckerman therapy at the UCSF Psoriasis Center were followed from admission to discharge. A total of 25 consecutive psoriasis patients were treated with the Goeckerman regimen until (near-) clearance or for a maximum period of 3 months, and their weekly improvements in terms of PASI (psoriasis area and severity index) were recorded. RESULTS: In all, 100% reached PASI 75 by 12 weeks of treatment. In fact, by 8 weeks, 95% reached PASI 75 and most of the patients were discharged within 2 months. CONCLUSIONS: The onset of treatment effect was rapid. Goeckerman therapy is still a valuable and important part of the psoriatic armamentarium.
BACKGROUND: Compared with the original Goeckerman therapy devised by Dr Goeckerman in the 1930s, modern modified Goeckerman therapy in the second millennium shows significantly enhanced efficacy by improvements in technology (e.g. narrowband UVB) and the possibility of adding other relatively safe therapeutic options for more resistant cases to enhance efficacy without compromising the basic safety profile. METHODS: For approximately 6 months, psoriasispatients undergoing Goeckerman therapy at the UCSF Psoriasis Center were followed from admission to discharge. A total of 25 consecutive psoriasispatients were treated with the Goeckerman regimen until (near-) clearance or for a maximum period of 3 months, and their weekly improvements in terms of PASI (psoriasis area and severity index) were recorded. RESULTS: In all, 100% reached PASI 75 by 12 weeks of treatment. In fact, by 8 weeks, 95% reached PASI 75 and most of the patients were discharged within 2 months. CONCLUSIONS: The onset of treatment effect was rapid. Goeckerman therapy is still a valuable and important part of the psoriatic armamentarium.
Authors: Tomas Toledo-Pastrana; María José García-Hernández; Ana María Carrizosa-Esquivel; Francisco Miguel Camacho-Martínez Journal: An Bras Dermatol Date: 2015 Jul-Aug Impact factor: 1.896
Authors: Tian Hao Zhu; Mio Nakamura; Benjamin Farahnik; Michael Abrouk; Rasnik K Singh; Kristina M Lee; Sarah Hulse; John Koo; Tina Bhutani; Wilson Liao Journal: Dermatol Ther (Heidelb) Date: 2016-07-29