Literature DB >> 16018641

Highly stereoselective synthesis of 2,5-disubstituted 3-vinylidene tetetrahydrofurans via Prins-type cyclization.

Chul Shin1, Satish N Chavre, Ae Nim Pae, Joo Hwan Cha, Hun Yeong Koh, Moon Ho Chang, Jung Hoon Choi, Yong Seo Cho.   

Abstract

[reaction: see text]. A novel synthetic methodology for 2,5-disubstituted tetrahydrofurans having an allenyl group at the 3-position via Prins-type cyclization was developed. The reaction led to excellent selectivity and moderate to high yields.

Entities:  

Year:  2005        PMID: 16018641     DOI: 10.1021/ol051058r

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  [2-(4-Chloro-phen-yl)-5-phenyl-oxolan-3-yl](cyclo-penten-yl)methanone.

Authors:  Jae Kyun Lee; Satish N Chavre; Yong Seo Cho; Yeonhee Lee; Joo Hwan Cha
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-12-07
  1 in total

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