Literature DB >> 16018330

Subanesthetic ketamine: how it alters physiology and behavior in humans.

Laura M Rowland1.   

Abstract

Ketamine is a drug that is commonly used for anesthesia and analgesia worldwide. Although it has an excellent safety profile, cognitive and psychotomimetic adverse effects are commonly associated with its administration. This review describes the clinical applications, potential adverse events, neurobiological, and behavioral effects of ketamine used at subanesthetic doses in humans.

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Year:  2005        PMID： 16018330

Source DB:  PubMed          Journal:  Aviat Space Environ Med        ISSN： 0095-6562


  21 in total

1.  Spatial memory deficits in a virtual reality eight-arm radial maze in schizophrenia.

Authors:  Elena A Spieker; Robert S Astur; Jeffrey T West; Jacqueline A Griego; Laura M Rowland
Journal:  Schizophr Res       Date:  2011-12-09       Impact factor: 4.939

2.  Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.

Authors:  Hongjie Yuan; Scott J Myers; Gordon Wells; Katherine L Nicholson; Sharon A Swanger; Polina Lyuboslavsky; Yesim A Tahirovic; David S Menaldino; Thota Ganesh; Lawrence J Wilson; Dennis C Liotta; James P Snyder; Stephen F Traynelis
Journal:  Neuron       Date:  2015-02-26       Impact factor: 17.173

3.  Mechanistic studies on ketamine-induced mitochondrial toxicity in zebrafish embryos.

Authors:  Bonnie L Robinson; Melanie Dumas; Syed F Ali; Merle G Paule; Qiang Gu; Jyotshna Kanungo
Journal:  Neurotoxicol Teratol       Date:  2017-12-07       Impact factor: 3.763

4.  Distinct effects of ketamine and acetyl L-carnitine on the dopamine system in zebrafish.

Authors:  Bonnie L Robinson; Melanie Dumas; Elvis Cuevas; Qiang Gu; Merle G Paule; Syed F Ali; Jyotshna Kanungo
Journal:  Neurotoxicol Teratol       Date:  2016-02-16       Impact factor: 3.763

Review 5.  Development of allosteric modulators of GPCRs for treatment of CNS disorders.

Authors:  Hilary Highfield Nickols; P Jeffrey Conn
Journal:  Neurobiol Dis       Date:  2013-09-27       Impact factor: 5.996

Review 6.  Reviewing the ketamine model for schizophrenia.

Authors:  Joel Frohlich; John D Van Horn
Journal:  J Psychopharmacol       Date:  2013-11-20       Impact factor: 4.153

7.  Cyclosporine exacerbates ketamine toxicity in zebrafish: Mechanistic studies on drug-drug interaction.

Authors:  Bonnie L Robinson; Melanie Dumas; Syed F Ali; Merle G Paule; Qiang Gu; Jyotshna Kanungo
Journal:  J Appl Toxicol       Date:  2017-06-01       Impact factor: 3.446

8.  Acetyl L-carnitine targets adenosine triphosphate synthase in protecting zebrafish embryos from toxicities induced by verapamil and ketamine: An in vivo assessment.

Authors:  Xiaoqing Guo; Melanie Dumas; Bonnie L Robinson; Syed F Ali; Merle G Paule; Qiang Gu; Jyotshna Kanungo
Journal:  J Appl Toxicol       Date:  2016-05-18       Impact factor: 3.446

9.  Opposing effects of ketamine and acetyl L-carnitine on the serotonergic system of zebrafish.

Authors:  Bonnie L Robinson; Melanie Dumas; Merle G Paule; Syed F Ali; Jyotshna Kanungo
Journal:  Neurosci Lett       Date:  2015-09-10       Impact factor: 3.046

10.  The interactive effects of ketamine and nicotine on human cerebral blood flow.

Authors:  Laura M Rowland; Lori Beason-Held; Carol A Tamminga; Henry H Holcomb
Journal:  Psychopharmacology (Berl)       Date:  2010-03       Impact factor: 4.530
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