Literature DB >> 16015693

Surgical experience in splitting donor liver into left lateral and right extended lobes.

Ji-Qi Yan1, Thomas Becker, Michael Neipp, Cheng-Hong Peng, Rainer Lueck, Frank Lehner, Hong-Wei Li, Juergen Klempnauer.   

Abstract

AIM: To outline the surgical experience with donor liver splitting in split liver transplantation.
METHODS: From March 1 to September 1 in 2004, 10 donor livers were split ex situ into a left lateral lobe (segments II and III) and a right extended lobe (segments I, IV-VIII) in Medical School of Hannover, and thereafter split liver transplantation was performed successfully in 19 cases. The average age, weight and ICU staying period of the donors were 32.7 years (15-51 years), 64.5 kg (45-75 kg) and 2.4 d (1-8 d) respectively.
RESULTS: The average weight of the whole graft and the left lateral lobe was 1,322.6 g (956-1,665 g) and 281.8 g (198-373 g) respectively, and the average ratio of left lateral lobe to the whole graft was 0.215 (0.178-0.274). The average graft to recipient weight ratio (GRWR) of the left lateral lobe and the right extended lobe reached 2.44% (1.22-5.41%) and 1.73% (1.31-2.30%) respectively. On average it took approximately 105 min (85-135 min) to split the donor liver. Five donor organs showed anatomic variation including the left hepatic vein variation in two cases, the left hepatic artery variation in two cases and the bile duct variation in one case.
CONCLUSION: Split liver transplantation has become a mature surgical technique to expand the donor pool with promising results. In the process of graft splitting, close attention needs to be paid to potential anatomic variations, especially to variations of the left hepatic vein, the left hepatic artery, and the bile duct.

Entities:  

Mesh:

Year:  2005        PMID: 16015693      PMCID: PMC4615446          DOI: 10.3748/wjg.v11.i27.4220

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  28 in total

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Authors:  Y Kawarada; B C Das; H Taoka
Journal:  J Hepatobiliary Pancreat Surg       Date:  2000

2.  Technical and logistical considerations of in situ split-liver transplantation for two adults: Part II. Creation of left segment I-IV and right segment V-VIII grafts.

Authors:  Hasan Yersiz; John F Renz; Garrett Hisatake; Paulo R Reichert; Nicholas J Feduska; Susan Lerner; Douglas G Farmer; R Mark Ghobrial; Sunil Geevarghese; Angeles Baquerizo; Pauline Chen; Ronald W Busuttil
Journal:  Liver Transpl       Date:  2002-01       Impact factor: 5.799

3.  Liver transplantation today.

Authors:  J Klempnauer; H Schrem; T Becker; B Nashan; R Lück
Journal:  Transplant Proc       Date:  2001 Nov-Dec       Impact factor: 1.066

Review 4.  Split-liver transplantation: a review.

Authors:  John F Renz; Hasan Yersiz; Paulo R Reichert; Garrett M Hisatake; Douglas G Farmer; Jean C Emond; Ronald W Busuttil
Journal:  Am J Transplant       Date:  2003-11       Impact factor: 8.086

5.  Split-liver transplantation in the United States: outcomes of a national survey.

Authors:  John F Renz; Jean C Emond; Hasan Yersiz; Nancy L Ascher; Ronald W Busuttil
Journal:  Ann Surg       Date:  2004-02       Impact factor: 12.969

6.  Predictors of survival after In vivo split liver transplantation: analysis of 110 consecutive patients.

Authors:  R M Ghobrial; H Yersiz; D G Farmer; F Amersi; J Goss; P Chen; S Dawson; S Lerner; N Nissen; D Imagawa; S Colquhoun; W Arnout; S V McDiarmid; R W Busuttil
Journal:  Ann Surg       Date:  2000-09       Impact factor: 12.969

7.  Intrahepatic portal venous variations: prevalence with US.

Authors:  M Atri; P M Bret; M A Fraser-Hill
Journal:  Radiology       Date:  1992-07       Impact factor: 11.105

8.  Results in split liver transplantation.

Authors:  A Moreno; J C Meneu; E Moreno; I Garcia; C Loinaz; C Jimenez; R Gómez; M Abradelo; J Calvo; Y Fundora; C Ortiz
Journal:  Transplant Proc       Date:  2003-08       Impact factor: 1.066

Review 9.  Optimizing the use of donated cadaver livers: analysis and policy development to increase the application of split-liver transplantation.

Authors:  Jean C Emond; Richard B Freeman; John F Renz; Hasan Yersiz; Xavier Rogiers; Ronald W Busuttil
Journal:  Liver Transpl       Date:  2002-10       Impact factor: 5.799

10.  Size reduction of the donor liver is a safe way to alleviate the shortage of size-matched organs in pediatric liver transplantation.

Authors:  J B Otte; J de Ville de Goyet; E Sokal; D Alberti; D Moulin; B de Hemptinne; F Veyckemans; L van Obbergh; M Carlier; P Clapuyt
Journal:  Ann Surg       Date:  1990-02       Impact factor: 12.969

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