Literature DB >> 16015552

Experience with docetaxel in the treatment of gastric cancer.

Philip A Philip1.   

Abstract

Gastric cancer is the second most common cause of cancer death worldwide. In operable patients, standard care includes surgery with or without adjuvant chemotherapy and radiotherapy; standard care for inoperable disease includes chemotherapy with or without radiotherapy. Docetaxel has shown in vitro and in vivo antitumor effects on human gastric cell lines and gastric cancer xenografts. Phase I through III trials of docetaxel alone and in combination with other chemotherapy agents have subsequently been conducted. This review provides an overview of these studies and suggestions for future directions in the treatment of gastric cancer.

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Year:  2005        PMID： 16015552     DOI： 10.1053/j.seminoncol.2005.04.004

Source DB:  PubMed          Journal:  Semin Oncol        ISSN： 0093-7754            Impact factor:   4.929


  6 in total

1.  Evaluation of Cassia occidentalis for in vitro cytotoxicity against human cancer cell lines and antibacterial activity.

Authors:  Madhulika Bhagat; Ajit Kumar Saxena
Journal:  Indian J Pharmacol       Date:  2010-08       Impact factor: 1.200

2.  Catharanthus roseus Aqueous Extract is Cytotoxic to Jurkat Leukaemic T-cells but Induces the Proliferation of Normal Peripheral Blood Mononuclear Cells.

Authors:  Nor Hazwani Ahmad; Rohanizah Abdul Rahim; Ishak Mat
Journal:  Trop Life Sci Res       Date:  2010-12

3.  A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation.

Authors:  Eva Jiménez-Medina; Angel Garcia-Lora; Laura Paco; Ignacio Algarra; Antonia Collado; Federico Garrido
Journal:  BMC Cancer       Date:  2006-05-05       Impact factor: 4.430

4.  In vivo antitumor potential of Ipomoea pes-caprae on melanoma cancer.

Authors:  Ashish Manigauha; M D Kharya; N Ganesh
Journal:  Pharmacogn Mag       Date:  2015 Apr-Jun       Impact factor: 1.085

5.  A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent.

Authors:  Manish S Lavhale; Santosh Kumar; Shri Hari Mishra; Sandhya L Sitasawad
Journal:  PLoS One       Date:  2009-04-28       Impact factor: 3.240

6.  Histological complete response to a combined docetaxel/cisplatin/fluorouracil neoadjuvant chemotherapy for T4 stage gastric adenocarcinoma.

Authors:  Ming gao Guo; Qi Zheng; Jian zhong Di; Zhe Yang
Journal:  World J Surg Oncol       Date:  2014-05-19       Impact factor: 2.754
  6 in total

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