Literature DB >> 16010365

First total synthesis of cichorine and zinnimidine.

Anne Moreau1, Axel Couture, Eric Deniau, Pierre Grandclaudon, Stéphane Lebrun.   

Abstract

The first total synthesis of the phytotoxins cichorine and zinnimidine is described. The synthetic tactics involve the sequential connection of the dense and diverse functionalities on the aromatic nucleus followed by a Parham cyclization process, giving rise to the lactam unit embedded in the title compound framework.

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Year:  2005        PMID: 16010365     DOI: 10.1039/b504602e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans.

Authors:  James F Sanchez; Ruth Entwistle; David Corcoran; Berl R Oakley; Clay C C Wang
Journal:  Medchemcomm       Date:  2012-08-01       Impact factor: 3.597

  1 in total

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