Literature DB >> 16010012

TAT-mediated protein transduction: delivering biologically active proteins to the heart.

Asa B Gustafsson1, Roberta A Gottlieb, David J Granville.   

Abstract

TAT protein transduction is a novel method of delivering biologically active proteins into cells and tissues through the fusion of a protein transduction domain to the protein of interest. The present chapter outlines the methodology pertaining to the preparation of TAT-fusion proteins and how to efficiently transduce these proteins into cultured cells or isolated rat hearts perfused in Langendorff mode.

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Year:  2005        PMID: 16010012

Source DB:  PubMed          Journal:  Methods Mol Med        ISSN: 1543-1894


  9 in total

1.  TAT opens the door.

Authors:  Piyush M Vyas; Ronald M Payne
Journal:  Mol Ther       Date:  2008-04       Impact factor: 11.454

2.  Cardiomyopathy of Friedreich's ataxia: use of mouse models to understand human disease and guide therapeutic development.

Authors:  R Mark Payne; P Melanie Pride; Clifford M Babbey
Journal:  Pediatr Cardiol       Date:  2011-03-01       Impact factor: 1.655

3.  Novel peptide for attenuation of hyperoxia-induced disruption of lung endothelial barrier and pulmonary edema via modulating peroxynitrite formation.

Authors:  Dmitry Kondrikov; Christine Gross; Stephen M Black; Yunchao Su
Journal:  J Biol Chem       Date:  2014-10-14       Impact factor: 5.157

4.  Endotoxin deactivation by transient acidification.

Authors:  Melina M Ribeiro; Xiumin Xu; Dagmar Klein; Norma S Kenyon; Camillo Ricordi; Maria Sueli S Felipe; Ricardo L Pastori
Journal:  Cell Transplant       Date:  2010-04-21       Impact factor: 4.064

5.  Beta-actin association with endothelial nitric-oxide synthase modulates nitric oxide and superoxide generation from the enzyme.

Authors:  Dmitry Kondrikov; Fabio V Fonseca; Shawn Elms; David Fulton; Steven M Black; Edward R Block; Yunchao Su
Journal:  J Biol Chem       Date:  2009-11-28       Impact factor: 5.157

6.  Tumor necrosis factor-alpha-induced sickness behavior is impaired by central administration of an inhibitor of c-jun N-terminal kinase.

Authors:  K Palin; R H McCusker; K Strle; F Moos; R Dantzer; K W Kelley
Journal:  Psychopharmacology (Berl)       Date:  2008-02-12       Impact factor: 4.530

7.  Xenotransplantation of mitochondrial electron transfer enzyme, Ndi1, in myocardial reperfusion injury.

Authors:  Cynthia N Perry; Chengqun Huang; Wayne Liu; Najib Magee; Raquel Sousa Carreira; Roberta A Gottlieb
Journal:  PLoS One       Date:  2011-02-14       Impact factor: 3.240

8.  Investigation of the synergistic effects of haloperidol combined with Calculus Bovis Sativus in treating MK-801-induced schizophrenia in rats.

Authors:  Kai Lei; Guo-Fang He; Cheng-Liang Zhang; Ya-Nan Liu; Juan Li; Guang-Zhao He; Xi-Ping Li; Xiu-Hua Ren; Dong Liu
Journal:  Exp Anim       Date:  2017-12-08

9.  One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli.

Authors:  Laura Caldinelli; Diego Albani; Loredano Pollegioni
Journal:  BMC Biotechnol       Date:  2013-04-04       Impact factor: 2.563

  9 in total

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