| Literature DB >> 16009537 |
R Wielgo-Polanin1, L Lagarce, E Gautron, B Diquet, P Lainé-Cessac.
Abstract
Here we report on a case of hepatotoxicity associated with the use of a fixed combination of chloroquine and proguanil. Alternative causes of liver injury were excluded. The pathophysiological mechanism remains unclear, with a possibility of allergic reaction. In view of the widespread use of both drugs, clinicians should be aware of this drug-induced liver injury.Entities:
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Year: 2005 PMID: 16009537 DOI: 10.1016/j.ijantimicag.2005.04.019
Source DB: PubMed Journal: Int J Antimicrob Agents ISSN: 0924-8579 Impact factor: 5.283