Pathophysiologic changes of obesity.

This article builds on the well-known changes that occur with obesity by drawing from recent advances reported in the literature for an improved understanding of obese patients. The dissemination of information regarding the health risks with being overweight or obese to both the public and the health care community are widespread and effective from a public health perspective. The mechanisms underlying these associated risks must continue to be explored for physicians' knowledge to truly increase, and lead to advances in our understanding of the pathophysiology of obesity.