Literature DB >> 16005212

Inhibition of tumor cell proliferation by thieno[2,3-d]pyrimidin-4(1H)-one-based analogs.

Yanong D Wang1, Steven Johnson, Dennis Powell, John P McGinnis, Miriam Miranda, Sridhar K Rabindran.   

Abstract

On the basis of a screening lead from an assay using a pair of p21 isogenic cell lines (p21-proficient cells and p21-deficient cells) to identify chemoselective agents, a series of novel thieno[2,3-d]pyrimidin-4(1H)-one-based analogs was prepared. Some analogs inhibited the growth of human colon tumor cells.

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Year:  2005        PMID: 16005212     DOI: 10.1016/j.bmcl.2005.05.127

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

1.  Targeted Synthesis and Study of Anti-tyrosinase Activity of 2-Substituted Tetrahydrobenzo[4,5]Thieno[2,3-d]Pyrimidine-4(3H)-One.

Authors:  Alexey Chiriapkin; Ivan Kodonidi; Dmitry Pozdnyakov
Journal:  Iran J Pharm Res       Date:  2022-05-13       Impact factor: 1.962

2.  Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents.

Authors:  Yahia Nasser Mabkhot; Fatima Alatibi; Nahed Nasser E El-Sayed; Nabila Abdelshafy Kheder; Salim S Al-Showiman
Journal:  Molecules       Date:  2016-08-09       Impact factor: 4.411

3.  From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors.

Authors:  Serena Massari; Angela Corona; Simona Distinto; Jenny Desantis; Alessia Caredda; Stefano Sabatini; Giuseppe Manfroni; Tommaso Felicetti; Violetta Cecchetti; Christophe Pannecouque; Elias Maccioni; Enzo Tramontano; Oriana Tabarrini
Journal:  J Enzyme Inhib Med Chem       Date:  2019-12       Impact factor: 5.051

Review 4.  Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer.

Authors:  Kasipandi Muniyandi; Blassan George; Thangaraj Parimelazhagan; Heidi Abrahamse
Journal:  Molecules       Date:  2020-09-08       Impact factor: 4.411

  4 in total

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