Literature DB >> 16003841

Antileishmanial agents part-IV: synthesis and antileishmanial activity of novel terpenyl pyrimidines.

Naveen Chandra1, Neena Goyal, S N Suryawanshi, Suman Gupta.   

Abstract

Some novel N- and O-substituted terpenyl pyrimidines 4 (a-j) have been synthesized and screened for in vitro antileishmanial activity profile in promastigote model. Some of the compounds exhibited 100% inhibition at 10 microg ml(-1) concentration.

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Year:  2005        PMID： 16003841     DOI： 10.1016/j.ejmech.2005.01.004

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  4 in total

1.  Use of Leishmania donovani field isolates expressing the luciferase reporter gene in in vitro drug screening.

Authors:  Suman Gupta; Shyam Sundar; Neena Goyal
Journal:  Antimicrob Agents Chemother       Date:  2005-09       Impact factor: 5.191

2.  Synthesis of a new series of substituted pyrimidines and its evaluation for antibacterial and antinociceptive effects.

Authors:  Akhlaq Waheed; Mohammad S Alorainy; Abdullah A Alghasham; Suroor A Khan; Muhammad Raza
Journal:  Int J Health Sci (Qassim)       Date:  2008-01

Review 3.  Significance and biological importance of pyrimidine in the microbial world.

Authors:  Vinita Sharma; Nitin Chitranshi; Ajay Kumar Agarwal
Journal:  Int J Med Chem       Date:  2014-03-23

4.  Past and future of trypanosomatids high-throughput phenotypic screening.

Authors:  Rafael Ferreira Dantas; Eduardo Caio Torres-Santos; Floriano Paes Silva
Journal:  Mem Inst Oswaldo Cruz       Date:  2022-03-11       Impact factor: 2.743
  4 in total

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