BACKGROUND: Cervical immature teratoma is a rare congenital tumor, and very few cases have been studied cytogenetically. CASE: In this article, we describe a case of this tumor type and present the findings of the karyotype of the lesion, which was performed with the bacterial artificial chromosome arrays using the comparative genomic hybridization method. The chromosomal abnormalities that we found included an amplification on 1p21.1, a 9p22 deletion, and a 1-copy gain of 17q21.33. CONCLUSIONS: None of the identified chromosomal aberrations have been previously associated with congenital extragonadal teratomas. Important genes that lie in these DNA regions may be implicated in the pathogenesis of congenital teratomas. Copyright 2005 Wiley-Liss, Inc.
BACKGROUND: Cervical immature teratoma is a rare congenital tumor, and very few cases have been studied cytogenetically. CASE: In this article, we describe a case of this tumor type and present the findings of the karyotype of the lesion, which was performed with the bacterial artificial chromosome arrays using the comparative genomic hybridization method. The chromosomal abnormalities that we found included an amplification on 1p21.1, a 9p22 deletion, and a 1-copy gain of 17q21.33. CONCLUSIONS: None of the identified chromosomal aberrations have been previously associated with congenital extragonadal teratomas. Important genes that lie in these DNA regions may be implicated in the pathogenesis of congenital teratomas. Copyright 2005 Wiley-Liss, Inc.
Authors: Ganesh Shankar; Michael R Rossi; Devin E McQuaid; Jeffrey M Conroy; Daniel G Gaile; John K Cowell; Norma J Nowak; Ping Liang Journal: Cancer Inform Date: 2006
Authors: Ori Hochwald; Ziv Gil; Arie Gordin; Zeev Winer; Ron Avrahami; Eitan Abargel; Asaad Khoury; Amit Lehavi; Philippe Abecassis; Liron Eldor; Ofer Ben-Izhak; Liron Borenstein-Levin; Ran Stienberg; Amir Kugelman Journal: J Med Case Rep Date: 2019-03-10