Literature DB >> 16001096

Recognizing and managing antipsychotic drug treatment side effects in the elderly.

Bruce L Saltz1, Delbert G Robinson, Margaret G Woerner.   

Abstract

Although atypical antipsychotics differ from conventional antipsychotics in their decreased ability to cause reversible drug-induced movement disorders/motor side effects such as dystonia, drug-induced parkinsonism, and akathisia and potentially persistent drug-induced movement disorders/motor side effects such as tardive dyskinesia, no antipsychotic agent completely eradicates this risk. Antipsychotic agents are frequently used in facilities for the elderly and in general hospitals to treat older patients with behavioral problems. Drug-induced movement disorders are more common and more persistent in elderly patients than in younger patients, and this problem is exacerbated by the fact that antipsychotic medications are often misused by practitioners lacking adequate psychopharmacologic training. Movement disorders can be detrimental to an elderly patient's quality of life and may transform what were otherwise routine activities into difficult tasks. Educational programs are needed to teach primary care physicians, specialists, and patients and their families how to identify and manage drug-induced movement disorders in order to achieve safer and more efficacious care for elderly patients.

Entities:  

Year:  2004        PMID: 16001096      PMCID: PMC487007     

Source DB:  PubMed          Journal:  Prim Care Companion J Clin Psychiatry        ISSN: 1523-5998


  15 in total

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  8 in total

Review 1.  Medication-Induced Tardive Dyskinesia: A Review and Update.

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2.  Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity.

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3.  Identification and management of adverse effects of antipsychotics in a tertiary care teaching hospital.

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4.  Blink rate is associated with drug-induced parkinsonism in patients with severe mental illness, but does not meet requirements to serve as a clinical test: the Curacao extrapyramidal syndromes study XIII.

Authors:  Charlotte L Mentzel; P Roberto Bakker; Jim van Os; Marjan Drukker; Glenn E Matroos; Marina A J Tijssen; Peter N van Harten
Journal:  J Negat Results Biomed       Date:  2017-08-25

5.  The effects of valbenazine on tardive dyskinesia in older and younger patients.

Authors:  Martha Sajatovic; George S Alexopoulos; Joshua Burke; Khodayar Farahmand; Scott Siegert
Journal:  Int J Geriatr Psychiatry       Date:  2019-10-31       Impact factor: 3.485

6.  Generalised tonic-clonic seizures on the subtherapeutic dose of olanzapine.

Authors:  Marium Mansoor; Mohammad Hanif Mesiya; Aisha Sanober Chachar
Journal:  BMJ Case Rep       Date:  2019-12-29

Review 7.  New and emerging treatments for symptomatic tardive dyskinesia.

Authors:  Abdul Qayyum Rana; Zishan M Chaudry; Pierre J Blanchet
Journal:  Drug Des Devel Ther       Date:  2013-11-06       Impact factor: 4.162

8.  Tardive dyskinesia occurring in a young woman after withdrawal of an atypical antipsychotic drug.

Authors:  Mohammed A Alblowi; Fahad D Alosaimi
Journal:  Neurosciences (Riyadh)       Date:  2015-10       Impact factor: 0.735

  8 in total

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