Literature DB >> 15999312

Use of an artificial dermis (Integra) for the reconstruction of extensive burn scars in children. About 22 grafts.

N Groos1, M Guillot, R Zilliox, F M Braye.   

Abstract

We used an artificial dermis (Integra) for the reconstruction of extensive burn scars in children. Integra was initially developed for the primary coverage of acute burns, but several authors report good experiences with Integra for reconstructive surgery. We present a group of 10 children who underwent Integra grafting at 22 different operational sites. Five children received several grafts with Integra. On average, 260 cm(2) per session were grafted. We compared the surface of Integra on the day of grafting and then again on the evaluation day to measure the secondary retraction of the grafts. Complications (infection of Integra, failure of the epidermal graft) were observed in 5 cases. At the final evaluation, 20 grafts were visible. The surface of the Integra graft represented less than 50% of the initial surface in 7 cases, 51-75% in 5 cases and more than 76% in 8 cases. The disadvantages of Integra in reconstructive surgery are that two operative procedures are necessary and the recurrence of contraction seems to be more significant than with full thickness auto grafts. However, Integra has many advantages: the immediate availability of large quantities, the simplicity and reliability of the technique, the pliability and the cosmetic aspect of the resulting coverage. In light of these preliminary results, Integra appears to offer a new alternative for the reconstruction of extensive burn scars in children.

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Year:  2005        PMID: 15999312     DOI: 10.1055/s-2004-821215

Source DB:  PubMed          Journal:  Eur J Pediatr Surg        ISSN: 0939-7248            Impact factor:   2.191


  7 in total

Review 1.  Comparison of Skin Substitutes for Acute and Chronic Wound Management.

Authors:  Caroline Bay; Zachary Chizmar; Edward M Reece; Jessie Z Yu; Julian Winocour; Joshua Vorstenbosch; Sebastian Winocour
Journal:  Semin Plast Surg       Date:  2021-09-10       Impact factor: 2.195

Review 2.  Infectious Complications Associated with the Use of Integra: A Systematic Review of the Literature.

Authors:  Santiago R Gonzalez; Keith G Wolter; James C Yuen
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-07-15

3.  Dermal regenerative matrix use in burn patients: A systematic review.

Authors:  Katie E Hicks; Minh Nq Huynh; Marc Jeschke; Claudia Malic
Journal:  J Plast Reconstr Aesthet Surg       Date:  2019-08-08       Impact factor: 2.740

4.  Versatile use of dermal substitutes: A retrospective survey of 127 consecutive cases.

Authors:  Giovanni Nicoletti; Marco Mario Tresoldi; Alberto Malovini; Marco Visaggio; Angela Faga; Silvia Scevola
Journal:  Indian J Plast Surg       Date:  2018 Jan-Apr

5.  Feasibility of the Use of RapiGraft and Skin Grafting in Reconstructive Surgery.

Authors:  Jung Dug Yang; In Gook Cho; Joon Hyun Kwon; Jeong Woo Lee; Kang Young Choi; Ho Yun Chung; Byung Chae Cho
Journal:  Arch Plast Surg       Date:  2016-09-21

Review 6.  Tissue engineering in burn scar reconstruction.

Authors:  Ppm van Zuijlen; Klm Gardien; Meh Jaspers; E J Bos; D C Baas; Ajm van Trier; E Middelkoop
Journal:  Burns Trauma       Date:  2015-09-30

7.  The importance of factorial design in tissue engineering and biomaterials science: Optimisation of cell seeding efficiency on dermal scaffolds as a case study.

Authors:  Alexandra Levin; Vaibhav Sharma; Lilian Hook; Elena García-Gareta
Journal:  J Tissue Eng       Date:  2018-06-25       Impact factor: 7.813

  7 in total

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