| Literature DB >> 15997857 |
Feng Wei1, Xian-Long Cheng, Lin-Yun Ma, Wen-Tao Jin, Brian T Schaneberg, Ikhlas A Khan, Rui-Chao Lin.
Abstract
An HPLC-UV-MS method for the analysis of aristolochic acids A, B, C and D, 7-OH-aristolochic acid A, and aristolic acid in a number of plant materials and their commercial products has been developed. HPLC with photodiode array detection and electrospray ionisation-MS in the selected ion monitoring mode allowed the identification of the target compounds and increased the selectivity of complex analyses such as those associated with multi-botanical preparations. The presented method was used to analyse 10 plant samples and six commercial products that possibly contained aristolochic acids. The resulting chromatographic profiles of the samples were significantly different from each other, and the method was directly transferred to HPLC-MS, which was used to confirm the presence of the six aristolochic acids mentioned above.Entities:
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Year: 2005 PMID： 15997857 DOI： 10.1002/pca.849
Source DB: PubMed Journal: Phytochem Anal ISSN： 0958-0344 Impact factor: 3.373