Literature DB >> 15996842

Bioguided isolation of pharmacologically active plant components, still a valuable strategy for the finding of new lead compounds?

Luc Pieters1, Arnold J Vlietinck.   

Abstract

The position of natural products research in the drug discovery and development process nowadays is discussed. A flow chart for the study of plants used in traditional medicine, and the composition of a multidisciplinary research team for the investigation of medicinal plants are presented, and some recommendations are made for the future of bioassay-guided isolations and the use of standardised plant extracts in developing countries.

Mesh：

Year:  2005        PMID： 15996842     DOI： 10.1016/j.jep.2005.05.029

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  17 in total

1.  The need for enhancement of research, development, and commercialization of natural medicinal products in Nigeria: lessons from the Malaysian experience.

Authors:  Bala Yauri Muhammad; Ahmed Awaisu
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-01-22

2.  Biological effects of Ocimum gratissimum L. are due to synergic action among multiple compounds present in essential oil.

Authors:  Luciane Almeida Galindo; Aline de Moraes Pultrini; Mirtes Costa
Journal:  J Nat Med       Date:  2010-06-18       Impact factor: 2.343

3.  Evaluation of the antioxidant, antibacterial, and antiproliferative activities of the acetone extract of the roots of Senna italica (Fabaceae).

Authors:  P Masoko; S S Gololo; M P Mokgotho; J N Eloff; R I Howard; L J Mampuru
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-12-30

4.  Comprehensive Phytochemical Profiling, Biological Activities, and Molecular Docking Studies of Pleurospermum candollei: An Insight into Potential for Natural Products Development.

Authors:  Maqsood Ahmed; Kashif-Ur-Rehman Khan; Saeed Ahmad; Hanan Y Aati; Chitchamai Ovatlarnporn; Muhammad Sajid-Ur Rehman; Tariq Javed; Anjum Khursheed; Bilal Ahmad Ghalloo; Rizwana Dilshad; Maryam Anwar
Journal:  Molecules       Date:  2022-06-26       Impact factor: 4.927

5.  Brazilian Organic Honey from Atlantic Rainforest Decreases Inflammatory Process in Mice.

Authors:  Diego Romário-Silva; Josy Goldoni Lazarini; Marcelo Franchin; Severino Matias de Alencar; Pedro Luiz Rosalen
Journal:  Vet Sci       Date:  2022-06-02

6.  Bioactivity-guided isolation and purification of α-glucosidase inhibitor, 6-O-D-glycosides, from Tinta Cão grape pomace.

Authors:  Shi Sun; Hoda Chaouki Kadouh; Wenjun Zhu; Kequan Zhou
Journal:  J Funct Foods       Date:  2016-03-31       Impact factor: 4.451

7.  New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants.

Authors:  Paul F Seke Etet; M Fawzi Mahomoodally
Journal:  ScientificWorldJournal       Date:  2012-04-19

Review 8.  Discovery of new anticancer agents from higher plants.

Authors:  Li Pan; Hee-Byung Chai; Alan Douglas Kinghorn
Journal:  Front Biosci (Schol Ed)       Date:  2012-01-01

9.  Evaluation of phytochemical content, antimicrobial, cytotoxic and antitumor activities of extract from Rumex hastatus D. Don roots.

Authors:  Sumaira Sahreen; Muhammad Rashid Khan; Rahmat Ali Khan; Taibi Ben Hadda
Journal:  BMC Complement Altern Med       Date:  2015-07-03       Impact factor: 3.659

Review 10.  Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites.

Authors:  Mahmoud Zaki El-Readi; Ahmed M Al-Abd; Mohammad A Althubiti; Riyad A Almaimani; Hiba Saeed Al-Amoodi; Mohamed Lotfy Ashour; Michael Wink; Safaa Yehia Eid
Journal:  Front Pharmacol       Date:  2021-05-21       Impact factor: 5.810
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