Literature DB >> 15996224

Granulysin: a novel host defense molecule.

Alan M Krensky1, Carol Clayberger.   

Abstract

Granulysin is a novel cationic molecule present in the granules of cytotoxic T lymphocytes and natural killer cells. Cytotoxic T lymphocytes have long been associated with graft destruction in transplant rejection. Recent studies implicate granulysin in cell-mediated cytotoxicity, chemoattraction, immune activation and as a potential diagnostic biomarker for transplant rejection.

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Year:  2005        PMID： 15996224     DOI： 10.1111/j.1600-6143.2005.00970.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN： 1600-6135            Impact factor:   8.086


  23 in total

1.  Expression and purification of 15 kDa granulysin utilizing an insect cell secretion system.

Authors:  Michael W Finn; Carol Clayberger; Alan M Krensky
Journal:  Protein Expr Purif       Date:  2010-07-30       Impact factor: 1.650

2.  Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria.

Authors:  Samuel J Balin; Matteo Pellegrini; Eynav Klechevsky; Sohui T Won; David I Weiss; Aaron W Choi; Joshua Hakimian; Jing Lu; Maria Teresa Ochoa; Barry R Bloom; Lewis L Lanier; Steffen Stenger; Robert L Modlin
Journal:  Sci Immunol       Date:  2018-08-31

3.  Granulysin production and anticryptococcal activity is dependent upon a far upstream enhancer that binds STAT5 in human peripheral blood CD4+ T cells.

Authors:  Junji Xing; Fuqing Wu; Shuai Wang; Alan M Krensky; Christopher H Mody; Chunfu Zheng
Journal:  J Immunol       Date:  2010-10-01       Impact factor: 5.422

4.  Present and future therapeutic strategies for melioidosis and glanders.

Authors:  D Mark Estes; Steven W Dow; Herbert P Schweizer; Alfredo G Torres
Journal:  Expert Rev Anti Infect Ther       Date:  2010-03       Impact factor: 5.091

5.  Increased granulysin expression in peripheral blood cells of patients with primary biliary cirrhosis and its clinical implications.

Authors:  Cheng Qian; Sunxiao Chen; Dingkang Yao; Chuanyong Wu; Tingwang Jiang; Jinshan Ke; Ye Zhou; Mingli Gu; Bo Chen; Anmei Deng; Renqian Zhong
Journal:  J Clin Immunol       Date:  2008-06-28       Impact factor: 8.317

6.  Biophysical analysis of the interaction of granulysin-derived peptides with enterobacterial endotoxins.

Authors:  Xi Chen; Jörg Howe; Jörg Andrä; Manfred Rössle; Walter Richter; Ana Paula Galvão da Silva; Alan M Krensky; Carol Clayberger; Klaus Brandenburg
Journal:  Biochim Biophys Acta       Date:  2007-05-22

Review 7.  Mucosal-associated invariant T cells from induced pluripotent stem cells: A novel approach for modeling human diseases.

Authors:  Chie Sugimoto; Hiroyoshi Fujita; Hiroshi Wakao
Journal:  World J Stem Cells       Date:  2016-04-26       Impact factor: 5.326

Review 8.  In vitro testing for the diagnosis of anticonvulsant hypersensitivity syndrome: a systematic review.

Authors:  Abdelbaset A Elzagallaai; Sandra R Knowles; Michael J Rieder; John R Bend; Neil H Shear; Gideon Koren
Journal:  Mol Diagn Ther       Date:  2009       Impact factor: 4.074

9.  Differential expression pattern of genes encoding for anti-microbial peptides in the fetal membranes of patients with spontaneous preterm labor and intact membranes and those with preterm prelabor rupture of the membranes.

Authors:  Offer Erez; Roberto Romero; Adi L Tarca; Tinnakorn Chaiworapongsa; Yeon Mee Kim; Nandor Gabor Than; Edi Vaisbuch; Sorin Draghici; Gerard Tromp
Journal:  J Matern Fetal Neonatal Med       Date:  2009-12

10.  Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.

Authors:  Thais F Galatro; Inge R Holtman; Antonio M Lerario; Ilia D Vainchtein; Nieske Brouwer; Paula R Sola; Mariana M Veras; Tulio F Pereira; Renata E P Leite; Thomas Möller; Paul D Wes; Mari C Sogayar; Jon D Laman; Wilfred den Dunnen; Carlos A Pasqualucci; Sueli M Oba-Shinjo; Erik W G M Boddeke; Suely K N Marie; Bart J L Eggen
Journal:  Nat Neurosci       Date:  2017-07-03       Impact factor: 24.884
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