M E Luchi1, R A Asherson, R G Lahita. 1. Department of Medicine, St. Luke's/Roosevelt Hospital, Columbia University, New York, New York 10019.
Abstract
OBJECTIVE: We report an unusual case of primary pulmonary hypertension and review the pertinent literature. METHODS: A 25-year-old Caucasian woman presented with progressive dyspnea and was found to have pulmonary hypertension. Antiphospholipid antibodies were present. The patient had a prolonged hospital course, was unresponsive to therapy, and died suddenly. RESULTS: Postmortem examination revealed a large thrombus affecting the right main pulmonary artery, with plexogenic arteriopathy bilaterally. CONCLUSION: This appears to be the first reported case of primary pulmonary hypertension complicated by thrombosis of a main pulmonary artery in association with antiphospholipid antibodies.
OBJECTIVE: We report an unusual case of primary pulmonary hypertension and review the pertinent literature. METHODS: A 25-year-old Caucasian woman presented with progressive dyspnea and was found to have pulmonary hypertension. Antiphospholipid antibodies were present. The patient had a prolonged hospital course, was unresponsive to therapy, and died suddenly. RESULTS: Postmortem examination revealed a large thrombus affecting the right main pulmonary artery, with plexogenic arteriopathy bilaterally. CONCLUSION: This appears to be the first reported case of primary pulmonary hypertension complicated by thrombosis of a main pulmonary artery in association with antiphospholipid antibodies.
Authors: M Okawa-Takatsuji; S Aotsuka; S Uwatoko; M Takaono; K Iwasaki; M Kinoshita; M Sumiya Journal: Clin Exp Immunol Date: 2001-11 Impact factor: 4.330