Literature DB >> 15995196

Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.

Takenori Satomura1, Daisuke Shimura, Kei Asai, Yoshito Sadaie, Kazutake Hirooka, Yasutaro Fujita.   

Abstract

During DNA microarray analysis, we discovered that the GlnK-GlnL (formerly YcbA-YcbB) two-component system positively regulates the expression of the glsA-glnT (formerly ybgJ-ybgH) operon in response to glutamine in the culture medium on Northern analysis. As a result of gel retardation and DNase I footprinting analyses, we found that the GlnL protein interacts with a region (bases -13 to -56; +1 is the transcription initiation base determined on primer extension analysis of glsA-glnT) in which a direct repeat, TTTTGTN4TTTTGT, is present. Furthermore, the glsA and glnT genes were biochemically verified to encode glutaminase and glutamine transporter, respectively.

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Year:  2005        PMID： 15995196      PMCID： PMC1169493          DOI： 10.1128/JB.187.14.4813-4821.2005

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  36 in total

Review 1.  NPS@: network protein sequence analysis.

Authors:  C Combet; C Blanchet; C Geourjon; G Deléage
Journal:  Trends Biochem Sci       Date:  2000-03       Impact factor: 13.807

2.  Bacillus subtilis glutamine synthetase controls gene expression through a protein-protein interaction with transcription factor TnrA.

Authors:  L V Wray; J M Zalieckas; S H Fisher
Journal:  Cell       Date:  2001-11-16       Impact factor: 41.582

3.  Mutations in the Bacillus subtilis glnRA operon that cause nitrogen source-dependent defects in regulation of TnrA activity.

Authors:  Susan H Fisher; Lewis V Wray
Journal:  J Bacteriol       Date:  2002-08       Impact factor: 3.490

4.  Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis.

Authors:  K Yoshida ; K Kobayashi; Y Miwa; C M Kang; M Matsunaga; H Yamaguchi; S Tojo; M Yamamoto; R Nishi; N Ogasawara; T Nakayama; Y Fujita
Journal:  Nucleic Acids Res       Date:  2001-02-01       Impact factor: 16.971

5.  Identification of two myo-inositol transporter genes of Bacillus subtilis.

Authors:  Ken-Ichi Yoshida; Yoshiyuki Yamamoto; Kaoru Omae; Mami Yamamoto; Yasutaro Fujita
Journal:  J Bacteriol       Date:  2002-02       Impact factor: 3.490

6.  Comprehensive DNA microarray analysis of Bacillus subtilis two-component regulatory systems.

Authors:  K Kobayashi; M Ogura; H Yamaguchi; K Yoshida; N Ogasawara; T Tanaka; Y Fujita
Journal:  J Bacteriol       Date:  2001-12       Impact factor: 3.490

7.  Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.

Authors:  K Yoshida; I Ishio; E Nagakawa; Y Yamamoto; M Yamamoto; Y Fujita
Journal:  Microbiology       Date:  2000-03       Impact factor: 2.777

8.  The periplasmic domain of the histidine autokinase CitA functions as a highly specific citrate receptor.

Authors:  S Kaspar; R Perozzo; S Reinelt; M Meyer; K Pfister; L Scapozza; M Bott
Journal:  Mol Microbiol       Date:  1999-08       Impact factor: 3.501

9.  Catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis.

Authors:  E Presecan-Siedel; A Galinier; R Longin; J Deutscher; A Danchin; P Glaser; I Martin-Verstraete
Journal:  J Bacteriol       Date:  1999-11       Impact factor: 3.490

10.  The CitST two-component system regulates the expression of the Mg-citrate transporter in Bacillus subtilis.

Authors:  H Yamamoto; M Murata; J Sekiguchi
Journal:  Mol Microbiol       Date:  2000-08       Impact factor: 3.501
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  22 in total

1.  CcpA-mediated catabolite activation of the Bacillus subtilis ilv-leu operon and its negation by either CodY- or TnrA-mediated negative regulation.

Authors:  Yasutaro Fujita; Takenori Satomura; Shigeo Tojo; Kazutake Hirooka
Journal:  J Bacteriol       Date:  2014-08-25       Impact factor: 3.490

2.  Regulation of nitrogenase by 2-oxoglutarate-reversible, direct binding of a PII-like nitrogen sensor protein to dinitrogenase.

Authors:  Jeremy A Dodsworth; John A Leigh
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-15       Impact factor: 11.205

3.  Structural classification of bacterial response regulators: diversity of output domains and domain combinations.

Authors:  Michael Y Galperin
Journal:  J Bacteriol       Date:  2006-06       Impact factor: 3.490

4.  Regulation of the Bacillus subtilis divergent yetL and yetM genes by a transcriptional repressor, YetL, in response to flavonoids.

Authors:  Kazutake Hirooka; Yusuke Danjo; Yuki Hanano; Satoshi Kunikane; Hiroshi Matsuoka; Shigeo Tojo; Yasutaro Fujita
Journal:  J Bacteriol       Date:  2009-03-27       Impact factor: 3.490

5.  Direct and indirect regulation of the ycnKJI operon involved in copper uptake through two transcriptional repressors, YcnK and CsoR, in Bacillus subtilis.

Authors:  Kazutake Hirooka; Takayosh Edahiro; Kosuke Kimura; Yasutaro Fujita
Journal:  J Bacteriol       Date:  2012-08-17       Impact factor: 3.490

6.  Uptake of amino acids and their metabolic conversion into the compatible solute proline confers osmoprotection to Bacillus subtilis.

Authors:  Adrienne Zaprasis; Monika Bleisteiner; Anne Kerres; Tamara Hoffmann; Erhard Bremer
Journal:  Appl Environ Microbiol       Date:  2014-10-24       Impact factor: 4.792

7.  Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.

Authors:  Greg Brown; Alex Singer; Michael Proudfoot; Tatiana Skarina; Youngchang Kim; Changsoo Chang; Irina Dementieva; Ekaterina Kuznetsova; Claudio F Gonzalez; Andrzej Joachimiak; Alexei Savchenko; Alexander F Yakunin
Journal:  Biochemistry       Date:  2008-05-06       Impact factor: 3.162

8.  Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.

Authors:  Ji-Yun Kim; Takashi Inaoka; Kazutaka Hirooka; Hiroshi Matsuoka; Makiko Murata; Reiko Ohki; Yoshikazu Adachi; Yasutaro Fujita; Kozo Ochi
Journal:  J Bacteriol       Date:  2009-03-13       Impact factor: 3.490

9.  Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in response to flavonoids.

Authors:  Kazutake Hirooka; Satoshi Kunikane; Hiroshi Matsuoka; Ken-Ichi Yoshida; Kanako Kumamoto; Shigeo Tojo; Yasutaro Fujita
Journal:  J Bacteriol       Date:  2007-05-04       Impact factor: 3.490

10.  Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine.

Authors:  Bang-Ce Ye; Yan Zhang; Hui Yu; Wen-Bang Yu; Bao-Hong Liu; Bin-Cheng Yin; Chun-Yun Yin; Yuan-Yuan Li; Ju Chu; Si-Liang Zhang
Journal:  PLoS One       Date:  2009-09-18       Impact factor: 3.240
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