Literature DB >> 15994836

Intrapatient escape in the A*0201-restricted epitope SLYNTVATL drives evolution of human immunodeficiency virus type 1 at the population level.

Charles T T Edwards1, Katja J Pfafferott, Philip J R Goulder, Rodney E Phillips, Edward C Holmes.   

Abstract

The hypothesis that the intrapatient emergence of cytotoxic T-lymphocyte escape variants contributes to the evolution of human immunodeficiency virus type 1 at the population (interpatient) level was tested using the HLA-A*0201-restricted gag p17 epitope SLYNTVATL. Using a simple experimental design, we investigated the evolutionary processes operating within this epitope among patients while compensating for the confounding influence of intrapatient natural selection. Using this approach, we revealed a pattern of A*0201-driven escape within patients, followed by the sustained transmission of these escape variants among patients irrespective of their HLA type.

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Year:  2005        PMID： 15994836      PMCID： PMC1168780          DOI： 10.1128/JVI.79.14.9363-9366.2005

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  24 in total

1.  Effect of recombination on the accuracy of the likelihood method for detecting positive selection at amino acid sites.

Authors:  Maria Anisimova; Rasmus Nielsen; Ziheng Yang
Journal:  Genetics       Date:  2003-07       Impact factor: 4.562

2.  HyPhy: hypothesis testing using phylogenies.

Authors:  Sergei L Kosakovsky Pond; Simon D W Frost; Spencer V Muse
Journal:  Bioinformatics       Date:  2004-10-27       Impact factor: 6.937

3.  Evolution and transmission of stable CTL escape mutations in HIV infection.

Authors:  P J Goulder; C Brander; Y Tang; C Tremblay; R A Colbert; M M Addo; E S Rosenberg; T Nguyen; R Allen; A Trocha; M Altfeld; S He; M Bunce; R Funkhouser; S I Pelton; S K Burchett; K McIntosh; B T Korber; B D Walker
Journal:  Nature       Date:  2001-07-19       Impact factor: 49.962

4.  Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation.

Authors:  P J Goulder; C Pasquier; E C Holmes; B Liang; Y Tang; J Izopet; K Saune; E S Rosenberg; S K Burchett; K McIntosh; M Barnardo; M Bunce; B D Walker; C Brander; R E Phillips
Journal:  Immunol Lett       Date:  2001-11-01       Impact factor: 3.685

5.  Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons.

Authors:  J G Garcia-Lerma; S Nidtha; K Blumoff; H Weinstock; W Heneine
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-06       Impact factor: 11.205

6.  Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences.

Authors:  C Brander; O O Yang; N G Jones; Y Lee; P Goulder; R P Johnson; A Trocha; D Colbert; C Hay; S Buchbinder; C C Bergmann; H J Zweerink; S Wolinsky; W A Blattner; S A Kalams; B D Walker
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

7.  Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus.

Authors:  Rajesh T Gandhi; Alysse Wurcel; Eric S Rosenberg; Mary N Johnston; Nicholas Hellmann; Michael Bates; Martin S Hirsch; Bruce D Walker
Journal:  Clin Infect Dis       Date:  2003-11-17       Impact factor: 9.079

8.  HIV evolution: CTL escape mutation and reversion after transmission.

Authors:  A J Leslie; K J Pfafferott; P Chetty; R Draenert; M M Addo; M Feeney; Y Tang; E C Holmes; T Allen; J G Prado; M Altfeld; C Brander; C Dixon; D Ramduth; P Jeena; S A Thomas; A St John; T A Roach; B Kupfer; G Luzzi; A Edwards; G Taylor; H Lyall; G Tudor-Williams; V Novelli; J Martinez-Picado; P Kiepiela; B D Walker; P J R Goulder
Journal:  Nat Med       Date:  2004-02-08       Impact factor: 53.440

9.  Advantage of rare HLA supertype in HIV disease progression.

Authors:  Elizabeth Trachtenberg; Bette Korber; Cristina Sollars; Thomas B Kepler; Peter T Hraber; Elizabeth Hayes; Robert Funkhouser; Michael Fugate; James Theiler; Yen S Hsu; Kevin Kunstman; Samuel Wu; John Phair; Henry Erlich; Steven Wolinsky
Journal:  Nat Med       Date:  2003-07       Impact factor: 53.440

10.  Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

Authors:  A D Kelleher; C Long; E C Holmes; R L Allen; J Wilson; C Conlon; C Workman; S Shaunak; K Olson; P Goulder; C Brander; G Ogg; J S Sullivan; W Dyer; I Jones; A J McMichael; S Rowland-Jones; R E Phillips
Journal:  J Exp Med       Date:  2001-02-05       Impact factor: 14.307
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  7 in total

1.  Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.

Authors:  Angel Varela-Rohena; Peter E Molloy; Steven M Dunn; Yi Li; Megan M Suhoski; Richard G Carroll; Anita Milicic; Tara Mahon; Deborah H Sutton; Bruno Laugel; Ruth Moysey; Brian J Cameron; Annelise Vuidepot; Marco A Purbhoo; David K Cole; Rodney E Phillips; Carl H June; Bent K Jakobsen; Andrew K Sewell; James L Riley
Journal:  Nat Med       Date:  2008-11-09       Impact factor: 53.440

2.  Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study.

Authors:  Santiago Avila-Rios; Christopher E Ormsby; Jonathan M Carlson; Humberto Valenzuela-Ponce; Juan Blanco-Heredia; Daniela Garrido-Rodriguez; Claudia Garcia-Morales; David Heckerman; Zabrina L Brumme; Simon Mallal; Mina John; Enrique Espinosa; Gustavo Reyes-Teran
Journal:  Retrovirology       Date:  2009-08-10       Impact factor: 4.602

3.  Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.

Authors:  Zabrina L Brumme; Chanson J Brumme; Jonathan Carlson; Hendrik Streeck; Mina John; Quentin Eichbaum; Brian L Block; Brett Baker; Carl Kadie; Martin Markowitz; Heiko Jessen; Anthony D Kelleher; Eric Rosenberg; John Kaldor; Yuko Yuki; Mary Carrington; Todd M Allen; Simon Mallal; Marcus Altfeld; David Heckerman; Bruce D Walker
Journal:  J Virol       Date:  2008-07-09       Impact factor: 5.103

4.  HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.

Authors:  Aleksandr M Gorin; Yushen Du; Franklin Y Liu; Tian-Hao Zhang; Hwee L Ng; Christian Hofmann; William G Cumberland; Ren Sun; Otto O Yang
Journal:  PLoS Pathog       Date:  2017-08-07       Impact factor: 6.823

5.  Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses.

Authors:  Christopher W Pohlmeyer; Sarah B Laskey; Sarah E Beck; Daniel C Xu; Adam A Capoferri; Caroline C Garliss; Megan E May; Alison Livingston; Walt Lichmira; Richard D Moore; M Sue Leffell; Nicholas J Butler; Jennifer E Thorne; John A Flynn; Robert F Siliciano; Joel N Blankson
Journal:  PLoS One       Date:  2018-02-21       Impact factor: 3.240

6.  Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection.

Authors:  Jayna Raghwani; Samir Bhatt; Oliver G Pybus
Journal:  PLoS Comput Biol       Date:  2016-01-07       Impact factor: 4.475

7.  Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.

Authors:  David K Cole; Anna Fuller; Garry Dolton; Efthalia Zervoudi; Mateusz Legut; Kim Miles; Lori Blanchfield; Florian Madura; Christopher J Holland; Anna M Bulek; John S Bridgeman; John J Miles; Andrea J A Schauenburg; Konrad Beck; Brian D Evavold; Pierre J Rizkallah; Andrew K Sewell
Journal:  Front Immunol       Date:  2017-11-10       Impact factor: 7.561
  7 in total

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