| Literature DB >> 15993502 |
Alexios Sotiropoulos, Aristofanis Gikas, Sotirios Skourtis, Panagiotis Merkouris, Panagiotis Pentzeridis, Antonios Polydorou, Stavros Pappas.
Abstract
Our aim was to investigate the relationship between the serologic status concerning Chlamydia pneumoniae and Helicobacter pylori with the presence of coronary artery disease (CAD), which remain a controversial issue in literature. We studied 208 patients with CAD and 94 controls with no evidence of obstructive CAD; all of them angiographically confirmed. The seropositivity to C. pneumoniae was 91% in patients with CAD vs 86% in controls (P>0.05). The H. pylori seroprevalence rates were 77% and 68%, respectively (P>0.05). The multivariate analysis, adjusting for age, sex, educational level, diabetes, hypertension, obesity, smoking, family history of CAD and lipids, confirmed the results of univariate analysis. Therefore, this study adds evidence against the association of seropositivity to C. pneumoniae and H. pylori with angiographically documented CAD.Entities:
Mesh：
Year: 2005 PMID： 15993502 DOI： 10.1016/j.ijcard.2005.05.039
Source DB: PubMed Journal: Int J Cardiol ISSN： 0167-5273 Impact factor: 4.164