| Literature DB >> 15990730 |
Kazuhiko Nakamura1, Masato Kodaka, Ibrahim M El-Mehasseb, Alina Gajewska, Hiroaki Okuno, Ewa Ochwanowska, Bozena Witek, Henryk Kozłowski, Kazimierz Kochman.
Abstract
MALDI-TOF mass spectrometry, 1H NMR spectrometry, the continuous variation method and molecular modeling by MM3 calculation confirmed our earlier studies showing that gonadotropin-releasing hormone (GnRH) forms complex with copper(II) ion with the binding ratio 1:1. The copper(II) complex formed at physiological pH has a square planar configuration and GnRH complexes with nickel(II) and cobalt(II) ions are less stable than that of copper(II).Entities:
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Year: 2005 PMID： 15990730
Source DB: PubMed Journal: Neuro Endocrinol Lett ISSN： 0172-780X Impact factor: 0.765