Literature DB >> 15990719

The Neurobiology of Love.

Tobias Esch1, George B Stefano.   

Abstract

Love is a complex neurobiological phenomenon, relying on trust, belief, pleasure and reward activities within the brain, i.e., limbic processes. These processes critically involve oxytocin, vasopressin, dopamine, and serotonergic signaling. Moreover, endorphin and endogenous morphinergic mechanisms, coupled to nitric oxide autoregulatory pathways, play a role. Naturally rewarding or pleasurable activities are necessary for survival and appetitive motivation, usually governing beneficial biological behaviors like eating, sex, and reproduction. Yet, a broad basis of common signaling and beneficial neurobiological features exists with connection to the love concept, thereby combining physiological aspects related to maternal, romantic or sexual love and attachment with other healthy activities or neurobiological states. Medical practice can make use of this concept, i.e., mind/body or integrative medicine. Thus, love, pleasure, and lust have a stress-reducing and health-promoting potential, since they carry the ability to heal or facilitate beneficial motivation and behavior. In addition, love and pleasure ensure the survival of individuals and their species. After all, love is a joyful and useful activity that encompasses wellness and feelings of well-being.

Entities:  

Mesh:

Year:  2005        PMID: 15990719

Source DB:  PubMed          Journal:  Neuro Endocrinol Lett        ISSN: 0172-780X            Impact factor:   0.765


  22 in total

1.  Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context.

Authors:  Erina Hara; Lubica Kubikova; Neal A Hessler; Erich D Jarvis
Journal:  Eur J Neurosci       Date:  2007-06       Impact factor: 3.386

2.  Assessing visual requirements for social context-dependent activation of the songbird song system.

Authors:  Erina Hara; Lubica Kubikova; Neal A Hessler; Erich D Jarvis
Journal:  Proc Biol Sci       Date:  2009-01-22       Impact factor: 5.349

Review 3.  Love as a Modulator of Pain.

Authors:  Sofina Tamam; Asma Hayati Ahmad
Journal:  Malays J Med Sci       Date:  2017-06-30

4.  Preoccupation in an early-romantic relationship predicts experimental pain relief.

Authors:  Aneesha Nilakantan; Jarred Younger; Arthur Aron; Sean Mackey
Journal:  Pain Med       Date:  2014-04-09       Impact factor: 3.750

Review 5.  Dopamine, morphine, and nitric oxide: an evolutionary signaling triad.

Authors:  George B Stefano; Richard M Kream
Journal:  CNS Neurosci Ther       Date:  2009-11-13       Impact factor: 5.243

6.  Falling in love is associated with immune system gene regulation.

Authors:  Damian R Murray; Martie G Haselton; Melissa Fales; Steven W Cole
Journal:  Psychoneuroendocrinology       Date:  2018-10-02       Impact factor: 4.905

7.  Addicted to love: What is love addiction and when should it be treated?

Authors:  Brian D Earp; Olga A Wudarczyk; Bennett Foddy; Julian Savulescu
Journal:  Philos Psychiatr Psychol       Date:  2017-03

8.  The Effects of Romantic Love on Mentalizing Abilities.

Authors:  Rafael Wlodarski; Robin I M Dunbar
Journal:  Rev Gen Psychol       Date:  2014-12-01

9.  Examining the possible functions of kissing in romantic relationships.

Authors:  Rafael Wlodarski; Robin I M Dunbar
Journal:  Arch Sex Behav       Date:  2013-10-11

10.  The neurobiological link between compassion and love.

Authors:  Tobias Esch; George B Stefano
Journal:  Med Sci Monit       Date:  2011-02-25
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