Literature DB >> 15989944

Life, death, and ubiquitin: taming the mule.

Ayelet Shmueli1, Moshe Oren.   

Abstract

Ubiquitin-mediated protein degradation is an efficient way for the cell to get rid of unwanted proteins. A key player in this process is the E3 ubiquitin ligase. In this issue of Cell, and describe a new E3 ligase, ARF-BP1/Mule, which targets two very different substrates, p53 and Mcl-1, with completely different cellular outcomes.

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Year:  2005        PMID： 15989944     DOI： 10.1016/j.cell.2005.06.018

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  22 in total

1.  Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change.

Authors:  Ewen Gallagher; Min Gao; Yun-Cai Liu; Michael Karin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-30       Impact factor: 11.205

2.  Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1.

Authors:  A Laine; Z Ronai
Journal:  Oncogene       Date:  2006-08-21       Impact factor: 9.867

3.  Targeted polyubiquitylation of RASSF1C by the Mule and SCFβ-TrCP ligases in response to DNA damage.

Authors:  Xin Zhou; Ting-Ting Li; Xu Feng; Esther Hsiang; Yue Xiong; Kun-Liang Guan; Qun-Ying Lei
Journal:  Biochem J       Date:  2012-01-01       Impact factor: 3.857

4.  HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.

Authors:  Eun Ryoung Jang; Ping Shi; Jamal Bryant; Jing Chen; Vikas Dukhande; Matthew S Gentry; HyeIn Jang; Myoungkun Jeoung; Emilia Galperin
Journal:  Mol Cell Biol       Date:  2014-07-14       Impact factor: 4.272

5.  JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha.

Authors:  Jianhua Wang; Chuanyu Li; Yuelong Liu; Wan Mei; Shaohua Yu; Cunren Liu; Liming Zhang; Xu Cao; Robert P Kimberly; William Grizzle; Huang-Ge Zhang
Journal:  Am J Pathol       Date:  2006-09       Impact factor: 4.307

Review 6.  The role of ubiquitination in tumorigenesis and targeted drug discovery.

Authors:  Lu Deng; Tong Meng; Lei Chen; Wenyi Wei; Ping Wang
Journal:  Signal Transduct Target Ther       Date:  2020-02-29

Review 7.  Versatile functions of p53 protein in multicellular organisms.

Authors:  P M Chumakov
Journal:  Biochemistry (Mosc)       Date:  2007-12       Impact factor: 2.487

8.  Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.

Authors:  Guillaume P Leboucher; Yien Che Tsai; Mei Yang; Kristin C Shaw; Ming Zhou; Timothy D Veenstra; Michael H Glickman; Allan M Weissman
Journal:  Mol Cell       Date:  2012-06-28       Impact factor: 17.970

Review 9.  The chemosensitivity of testicular germ cell tumors.

Authors:  Ioannis A Voutsadakis
Journal:  Cell Oncol (Dordr)       Date:  2014-04-02       Impact factor: 6.730

10.  Genome-wide association study identified CNP12587 region underlying height variation in Chinese females.

Authors:  Yin-Ping Zhang; Fei-Yan Deng; Tie-Lin Yang; Feng Zhang; Xiang-Ding Chen; Hui Shen; Xue-Zheng Zhu; Qing Tian; Hong-Wen Deng
Journal:  PLoS One       Date:  2012-09-05       Impact factor: 3.240
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