Inter- and intramolecular radical couplings of ene-ynes or halo-alkenes promoted by an InCl3/MeONa/Ph2SiH2 system.

[reaction: see text] An effective generation of indium hydride (HInCl(2)) under nonacidic conditions is achieved by transmetalation between Ph(2)SiH(2) and InCl(2)OMe. The presented system achieves the titled coupling reactions in a radical manner. In particular, the nonacidic character enables the applications to acid-sensitive inter- and intramolecular ene-yne couplings.