Literature DB >> 15986934

Pregnancy after stem cell transplantation.

Tal Schechter1, Yaron Finkelstein, John Doyle, Gideon Koren.   

Abstract

QUESTION: A married woman under my care underwent successful bone marrow transplantation as part of treatment for a malignancy. She wishes to start a family. What are her chances? Are there risks? ANSWER: Success in becoming pregnant after stem cell transplantation depends on such factors as cumulative doses of chemotherapy and radiation and mother's age at time of transplant. There is increased risk of prematurity, low birth weight, and spontaneous abortion. Pregnancy should be managed as high risk.

Entities:  

Mesh：

Year:  2005        PMID： 15986934      PMCID： PMC1479532     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  15 in total

1.  Gonadal status and reproductive function following treatment for Hodgkin's disease in childhood: the Stanford experience.

Authors:  T T Ortin; C A Shostak; S S Donaldson
Journal:  Int J Radiat Oncol Biol Phys       Date:  1990-10       Impact factor: 7.038

2.  Pubertal development and fertility in children after bone marrow transplantation.

Authors:  A Cohen; M T Van-Lint; A Lavagetto; S Chiodi; S Spinelli; A Bacigalupo; C Romano
Journal:  Bone Marrow Transplant       Date:  1991       Impact factor: 5.483

3.  Successful pregnancy after allogeneic bone marrow transplantation for chronic myeloid leukaemia.

Authors:  H G Atkinson; J F Apperley; K Dawson; J M Goldman; R M Winston
Journal:  Lancet       Date:  1994-07-16       Impact factor: 79.321

4.  Ovarian recovery after total body irradiation and allogeneic bone marrow transplantation: long-term follow up of 79 females.

Authors:  S Spinelli; S Chiodi; A Bacigalupo; A Brasca; M V Menada; A R Petti; G Ravera; F Gualandi; M T VanLint; M Sessarego
Journal:  Bone Marrow Transplant       Date:  1994-09       Impact factor: 5.483

5.  Successful pregnancy after allogeneic bone marrow transplant with embryos isolated before transplant.

Authors:  J H Lipton; M Virro; H Solow
Journal:  J Clin Oncol       Date:  1997-11       Impact factor: 44.544

6.  Ovarian function following marrow transplantation for aplastic anemia or leukemia.

Authors:  J E Sanders; C D Buckner; D Amos; W Levy; F R Appelbaum; K Doney; R Storb; K M Sullivan; R P Witherspoon; E D Thomas
Journal:  J Clin Oncol       Date:  1988-05       Impact factor: 44.544

7.  Prospective study of pituitary-gonadal function to evaluate short-term effects of ablative chemotherapy or total body irradiation with autologous or allogenic marrow transplantation in post-menarcheal female patients.

Authors:  R Chatterjee; W Mills; M Katz; H H McGarrigle; A H Goldstone
Journal:  Bone Marrow Transplant       Date:  1994-05       Impact factor: 5.483

8.  Pregnancy outcome in patients treated for Hodgkin's disease.

Authors:  J Aisner; P H Wiernik; P Pearl
Journal:  J Clin Oncol       Date:  1993-03       Impact factor: 44.544

Review 9.  Mechanism and management of treatment-related gonadal failure in recipients of high dose chemoradiotherapy.

Authors:  J F Apperley; N Reddy
Journal:  Blood Rev       Date:  1995-06       Impact factor: 8.250

10.  Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation.

Authors:  J E Sanders; J Hawley; W Levy; T Gooley; C D Buckner; H J Deeg; K Doney; R Storb; K Sullivan; R Witherspoon; F R Appelbaum
Journal:  Blood       Date:  1996-04-01       Impact factor: 22.113
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  1 in total

Review 1.  Long-term health impacts of hematopoietic stem cell transplantation inform recommendations for follow-up.

Authors:  Smita Bhatia
Journal:  Expert Rev Hematol       Date:  2011-08       Impact factor: 2.929
  1 in total

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