Literature DB >> 15986181

Alicyclic beta-amino acids in Medicinal Chemistry.

A Kuhl1, M G Hahn, M Dumić, J Mittendorf.   

Abstract

The structural element of alicyclic beta-amino acids shows some remarkable biological effects: For some 5- and 6-membered beta-amino acids a unique anti fungal activity has been observed, 7-membered beta-amino acid derivatives have been investigated for neurological disorders. The application of 5-, 6- and 7-membered alicyclic beta-amino acids in Medicinal Chemistry will be reported. [structure: see text]

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Year:  2005        PMID: 15986181     DOI: 10.1007/s00726-005-0212-y

Source DB:  PubMed          Journal:  Amino Acids        ISSN: 0939-4451            Impact factor:   3.520


  13 in total

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Journal:  Mikrochim Acta       Date:  2019-11-30       Impact factor: 5.833

5.  Stereoselective synthesis of perillaldehyde-based chiral β-amino acid derivatives through conjugate addition of lithium amides.

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6.  New Morphiceptin Peptidomimetic Incorporating (1S,2R,3S,4S,5R)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic acid: Synthesis and Structural Study.

Authors:  Raquel Soengas; Marcos Lorca; Begoña Pampín; Víctor M Sánchez-Pedregal; Ramón J Estévez; Juan C Estévez
Journal:  Molecules       Date:  2020-06-01       Impact factor: 4.411

7.  Highly functionalized 1,2-diamino compounds through reductive amination of amino acid-derived β-keto esters.

Authors:  Paula Pérez-Faginas; M Teresa Aranda; M Teresa García-López; Lourdes Infantes; Asia Fernández-Carvajal; José Manuel González-Ros; Antonio Ferrer-Montiel; Rosario González-Muñiz
Journal:  PLoS One       Date:  2013-01-07       Impact factor: 3.240

8.  Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production.

Authors:  Sándor B Otvös; Adám Georgiádes; István M Mándity; Lóránd Kiss; Ferenc Fülöp
Journal:  Beilstein J Org Chem       Date:  2013-07-29       Impact factor: 2.883

9.  Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration.

Authors:  Michele Mari; Simone Lucarini; Francesca Bartoccini; Giovanni Piersanti; Gilberto Spadoni
Journal:  Beilstein J Org Chem       Date:  2014-08-26       Impact factor: 2.883

10.  Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical-radical coupling.

Authors:  Zijun Zhou; Yanjun Li; Bowen Han; Lei Gong; Eric Meggers
Journal:  Chem Sci       Date:  2017-06-15       Impact factor: 9.825

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