Literature DB >> 15986161

Improved routine bio-medical and bio-analytical online fluorescence measurements using fluorescence lifetime resolution.

Lutz Pfeifer1, Karsten Stein, Ute Fink, Alexander Welker, Bianca Wetzl, Petra Bastian, Otto S Wolfbeis.   

Abstract

Fluorescence techniques are widely used as sensitive detection methods in bio-analytics. The use of the bio-physical parameter fluorescence lifetime additional to the spectral characteristics of fluorescence has the potential to improve fluorescence-related detection methods in terms of selectivity in signal recognition, robustness against disturbing influences, and the accessibility of novel bio-chemical process parameters. This article describes the technical set up of a time-resolving instrument with either a fixed time-gated detection principle for improved evaluation of tissue metabolism by an online monitoring of the tissue autofluorescence or a direct fluorescence lifetime detection principle for lifetime-based fluorescent assays.

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Year:  2005        PMID： 15986161     DOI： 10.1007/s10895-005-2634-z

Source DB:  PubMed          Journal:  J Fluoresc        ISSN： 1053-0509            Impact factor:   2.217


  16 in total

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5.  Fluorescence lifetime imaging of free and protein-bound NADH.

Authors:  J R Lakowicz; H Szmacinski; K Nowaczyk; M L Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

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Journal:  Biomed Tech (Berl)       Date:  1997-03       Impact factor: 1.411

7.  Ratiometric methodology for NAD(P)H measurement in the perfused rat heart using surface fluorescence.

Authors:  D A Scott; L W Grotyohann; J Y Cheung; R C Scaduto
Journal:  Am J Physiol       Date:  1994-08

8.  Ultraviolet laser-induced fluorescence of colonic tissue: basic biology and diagnostic potential.

Authors:  K T Schomacker; J K Frisoli; C C Compton; T J Flotte; J M Richter; N S Nishioka; T F Deutsch
Journal:  Lasers Surg Med       Date:  1992       Impact factor: 4.025

9.  Nicotinamide adenine dinucleotide fluorescence spectroscopy and imaging of isolated cardiac myocytes.

Authors:  J Eng; R M Lynch; R S Balaban
Journal:  Biophys J       Date:  1989-04       Impact factor: 4.033

10.  Optical spectroscopic imaging for non-invasive evaluation of tissue oxygenation.

Authors:  H A Bruining; G J Pierik; C Ince; F Ashruf
Journal:  Chirurgie       Date:  1992
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  4 in total

1.  Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry.

Authors:  Kristin A Fletcher; Sayo O Fakayode; Mark Lowry; Sheryl A Tucker; Sharon L Neal; Irene W Kimaru; Matthew E McCarroll; Gabor Patonay; Philip B Oldham; Oleksandr Rusin; Robert M Strongin; Isiah M Warner
Journal:  Anal Chem       Date:  2006-06-15       Impact factor: 6.986

2.  Effect of polystyrene microsphere surface to fluorescence lifetime under two-photon excitation.

Authors:  Marko E Tirri; Rina Wahlroos; Niko J Meltola; Juha Toivonen; Pekka E Hänninen
Journal:  J Fluoresc       Date:  2006-09-16       Impact factor: 2.217

3.  Two-photon excited fluorescence lifetime measurements through a double-clad photonic crystal fiber for tissue micro-endoscopy.

Authors:  Florian Knorr; Diego R Yankelevich; Jing Liu; Sebastian Wachsmann-Hogiu; Laura Marcu
Journal:  J Biophotonics       Date:  2011-11-02       Impact factor: 3.207

Review 4.  Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis.

Authors:  A C Croce; G Bottiroli
Journal:  Eur J Histochem       Date:  2014-12-12       Impact factor: 3.188
  4 in total

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