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Literature DB >> 1598496

Production of interleukin 8 by cultured synovial cells in response to interleukin 1 and tumor necrosis factor.

K Hirota¹, T Akahoshi, H Endo, H Kondo, S Kashiwazaki.

Abstract

Both interleukin 1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha) stimulated the production of interleukin 8 (IL-8) by synovial cells in time and dose dependent manners. Enhanced chemotactic activity of polymorphonuclear cells (PMN) in culture supernatants of synovial cells was neutralized with anti-IL-8 antibody, thus showing synovial cells to be capable of secreting IL-8 which may contribute to PMN accumulation in rheumatoid inflamed joints.

Entities: Disease Gene

Mesh：

Substances：

Year: 1992 PMID： 1598496 DOI： 10.1007/bf00246871

Source DB: PubMed Journal: Rheumatol Int ISSN： 0172-8172 Impact factor: 2.631

19 in total

Review 1. Rheumatoid arthritis. Pathophysiology and implications for therapy.

Authors: E D Harris
Journal: N Engl J Med Date: 1990-05-03 Impact factor: 91.245

2. Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor.

Authors: Y Furutani; M Notake; M Yamayoshi; J Yamagishi; H Nomura; M Ohue; R Furuta; T Fukui; M Yamada; S Nakamura
Journal: Nucleic Acids Res Date: 1985-08-26 Impact factor: 16.971

3. Neutrophil stimulation by recombinant cytokines and a factor produced by IL-1-treated human synovial cell cultures.

Authors: M L Watson; G P Lewis; J Westwick
Journal: Immunology Date: 1988-12 Impact factor: 7.397

4. Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

Authors: J M Dayer; S M Krane; R G Russell; D R Robinson
Journal: Proc Natl Acad Sci U S A Date: 1976-03 Impact factor: 11.205

5. Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

Authors: C G Larsen; A O Anderson; J J Oppenheim; K Matsushima
Journal: Immunology Date: 1989-09 Impact factor: 7.397

6. Phagocytic and bacterial properties of normal human monocytes.

Authors: R T Steigbigel; L H Lambert; J S Remington
Journal: J Clin Invest Date: 1974-01 Impact factor: 14.808

7. Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

Authors: E R Pettipher; G A Higgs; B Henderson
Journal: Proc Natl Acad Sci U S A Date: 1986-11 Impact factor: 11.205

8. Production and characterization of recombinant human neutrophil chemotactic factor.

Authors: R Furuta; J Yamagishi; H Kotani; F Sakamoto; T Fukui; Y Matsui; Y Sohmura; M Yamada; T Yoshimura; C G Larsen
Journal: J Biochem Date: 1989-09 Impact factor: 3.387

9. Secretion of novel and homologous neutrophil-activating peptides by LPS-stimulated human endothelial cells.

Authors: J M Schröder; E Christophers
Journal: J Immunol Date: 1989-01-01 Impact factor: 5.422

10. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

Authors: J M Dayer; B Beutler; A Cerami
Journal: J Exp Med Date: 1985-12-01 Impact factor: 14.307

5 in total

Production of interleukin 8 by cultured synovial cells in response to interleukin 1 and tumor necrosis factor.

Review 1. Rheumatoid arthritis. Pathophysiology and implications for therapy.

2. Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor.

3. Neutrophil stimulation by recombinant cytokines and a factor produced by IL-1-treated human synovial cell cultures.

4. Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

5. Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

6. Phagocytic and bacterial properties of normal human monocytes.

7. Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

8. Production and characterization of recombinant human neutrophil chemotactic factor.

9. Secretion of novel and homologous neutrophil-activating peptides by LPS-stimulated human endothelial cells.

10. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1. Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA).

2. Antimonial therapy induces circulating proinflammatory cytokines in patients with cutaneous leishmaniasis.

3. Interleukin-8 is a cyclosporin A binding protein.

4. Experimental arthritis induced by continuous infusion of IL-8 into rabbit knee joints.

5. Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies.