| Literature DB >> 15983627 |
B J Donnelly1, J C Saliken, D S Ernst, B Weber, J W Robinson, P M A Brasher, M Rose, J Rewcastle.
Abstract
Despite improvements in treatment of localized prostate cancer, local recurrence remains a significant problem. A total of 46 patients with proven local cancer recurrence following external beam radiotherapy entered a prospective clinical trial using ultrasound-guided cryosurgery to ablate the residual prostate gland. Persistent complications included one urethra-rectal fistula, incontinence (2), retention (3), and treatment induced erectile dysfunction (7). Using the PSA definitions for biochemical failure as PSA>or=0.3 ng/ml, the Kaplan-Meier plots showed the incidence of patients to be free of biochemical recurrence at 51 and 44% at 1 and 2 y, respectively. For a PSA>or=1.0, the values at 1 and 2 y were 72 and 58%.Entities:
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Year: 2005 PMID： 15983627 DOI： 10.1038/sj.pcan.4500811
Source DB: PubMed Journal: Prostate Cancer Prostatic Dis ISSN： 1365-7852 Impact factor: 5.554