OBJECTIVE: To study on the anti-obesity effect of phillyrin in nutritive obesity mice. METHOD: The alimentary obesity model was established by hyperalimentation. The wet weight of fat, fat index, number of fat cells per unit visual field, Lee's index, jejunum microvillus area, serum triglyceride and cholesterol were selected to observe the anti-obesity effect of phillyrin. RESULT: Phillyrin could lower wet weight of fat (P < 0.01), fat index (P < 0.05 or P < 0.01), diameter of fat cell and Lee's index (P < 0.05), decrease the jejunum microvillus area, lower the level of serum triglyceride and cholesterol. CONCLUSION: Phillyrin has anti-obesity effect in nutritive obesity mice.
OBJECTIVE: To study on the anti-obesity effect of phillyrin in nutritive obesitymice. METHOD: The alimentary obesity model was established by hyperalimentation. The wet weight of fat, fat index, number of fat cells per unit visual field, Lee's index, jejunum microvillus area, serum triglyceride and cholesterol were selected to observe the anti-obesity effect of phillyrin. RESULT: Phillyrin could lower wet weight of fat (P < 0.01), fat index (P < 0.05 or P < 0.01), diameter of fat cell and Lee's index (P < 0.05), decrease the jejunum microvillus area, lower the level of serum triglyceride and cholesterol. CONCLUSION:Phillyrin has anti-obesity effect in nutritive obesitymice.
Authors: Wei Zhou; Xuan Xuan Zhu; Ai Ling Yin; Bao Chang Cai; Hai Dan Wang; Liuqing Di; Jin Jun Shan Journal: Pharmacogn Mag Date: 2014-01 Impact factor: 1.085