OBJECTIVE: To describe a huge congenital cervical rhabdomyosarcoma. METHODS: We were recently confronted with a case of fetal solid neck mass arising in one fetus of a twin pregnancy. Prenatally, the cervical tumor was consistent with teratoma, but it was diagnosed histologically as a rhabdomyosarcoma. Genetic amniocentesis showed a mosaic pattern consisting of 46,XY/46,XY,t(2;8)(q35;q21.2). RESULTS: EXIT procedure was proposed to the parents but declined. The twin with huge cervical tumor died in utero at 35 weeks' gestation due to hydrops fetalis. CONCLUSION: Fetal cervical rhabdomyosarcoma is an extremely rare condition that has not been previously reported, but should be considered in the presentation of fetal solid neck mass. (c) 2005 S. Karger AG, Basel
OBJECTIVE: To describe a huge congenital cervical rhabdomyosarcoma. METHODS: We were recently confronted with a case of fetal solid neck mass arising in one fetus of a twin pregnancy. Prenatally, the cervical tumor was consistent with teratoma, but it was diagnosed histologically as a rhabdomyosarcoma. Genetic amniocentesis showed a mosaic pattern consisting of 46,XY/46,XY,t(2;8)(q35;q21.2). RESULTS: EXIT procedure was proposed to the parents but declined. The twin with huge cervical tumor died in utero at 35 weeks' gestation due to hydrops fetalis. CONCLUSION:Fetal cervical rhabdomyosarcoma is an extremely rare condition that has not been previously reported, but should be considered in the presentation of fetal solid neck mass. (c) 2005 S. Karger AG, Basel
Authors: Janos Sumegi; Renae Streblow; Robert W Frayer; Paola Dal Cin; Andrew Rosenberg; Aurelia Meloni-Ehrig; Julia A Bridge Journal: Genes Chromosomes Cancer Date: 2010-03 Impact factor: 5.006
Authors: Juan Miguel Mosquera; Andrea Sboner; Lei Zhang; Naoki Kitabayashi; Chun-Liang Chen; Yun Shao Sung; Leonard H Wexler; Michael P LaQuaglia; Morris Edelman; Chandrika Sreekantaiah; Mark A Rubin; Cristina R Antonescu Journal: Genes Chromosomes Cancer Date: 2013-03-05 Impact factor: 5.006