Literature DB >> 15980613

Histological staining of amyloid-beta in mouse brains.

Einar M Sigurdsson1.   

Abstract

The increased availability of transgenic mouse models for studying human diseases is shifting the focus of many laboratories from in vitro to in vivo assays. The purpose of this chapter is to provide investigators with methods that will allow them to obtain well-preserved mouse brain sections to be stained with the standard histological dyes for amyloid, Congo red and thio-flavin-S. These sections can as well be used for immunohistological procedures that allow detection of amyloid-beta plaques as well as pre-amyloid deposits.

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Year:  2005        PMID: 15980613     DOI: 10.1385/1-59259-874-9:299

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  7 in total

1.  Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages.

Authors:  Ayodeji A Asuni; Allal Boutajangout; Henrieta Scholtzova; Elin Knudsen; Yong Sheng Li; David Quartermain; Blas Frangione; Thomas Wisniewski; Einar M Sigurdsson
Journal:  Eur J Neurosci       Date:  2006-11       Impact factor: 3.386

2.  A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice.

Authors:  Einar M Sigurdsson; Youssef Z Wadghiri; Lisa Mosconi; Jeffrey A Blind; Elin Knudsen; Ayodeji Asuni; Henrieta Scholtzova; Wai H Tsui; Yongsheng Li; Martin Sadowski; Daniel H Turnbull; Mony J de Leon; Thomas Wisniewski
Journal:  Neurobiol Aging       Date:  2007-02-08       Impact factor: 4.673

3.  Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI.

Authors:  Anne Bertrand; Umer Khan; Dung M Hoang; Dmitry S Novikov; Pavan Krishnamurthy; Hameetha B Rajamohamed Sait; Benjamin W Little; Einar M Sigurdsson; Youssef Z Wadghiri
Journal:  Neuroimage       Date:  2012-08-31       Impact factor: 6.556

4.  Neuroglobin attenuates beta-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo.

Authors:  Adil A Khan; Xiao Ou Mao; Surita Banwait; Kunlin Jin; David A Greenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-19       Impact factor: 11.205

5.  Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives.

Authors:  Stéphanie G Trouche; Ayodeji Asuni; Sylvie Rouland; Thomas Wisniewski; Blas Frangione; Jean-Michel Verdier; Einar M Sigurdsson; Nadine Mestre-Francés
Journal:  Vaccine       Date:  2008-12-27       Impact factor: 3.641

6.  Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine.

Authors:  Allal Boutajangout; Fernando Goni; Elin Knudsen; Fernanda Schreiber; Ayodeji Asuni; David Quartermain; Blas Frangione; Alejandro Chabalgoity; Thomas Wisniewski; Einar M Sigurdsson
Journal:  J Alzheimers Dis       Date:  2009       Impact factor: 4.472

7.  A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid β Aggregates.

Authors:  K Rajasekhar; Nagarjun Narayanaswamy; N Arul Murugan; Guanglin Kuang; Hans Ågren; T Govindaraju
Journal:  Sci Rep       Date:  2016-04-01       Impact factor: 4.379

  7 in total

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