Literature DB >> 15980386

Compound efflux in Helicobacter pylori.

Amy Kutschke1, Boudewijn L M de Jonge.   

Abstract

Susceptibility testing with a variety of structurally unrelated compounds showed that hefC in Helicobacter pylori is involved in multidrug efflux. This efflux was shown to depend on the proton motive force, as demonstrated by ethidium bromide accumulation experiments. Thus, H. pylori contains an active multidrug efflux mechanism.

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Year:  2005        PMID： 15980386      PMCID： PMC1168643          DOI： 10.1128/AAC.49.7.3009-3010.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

Review 1.  The structure and function of drug pumps.

Authors:  M I Borges-Walmsley; A R Walmsley
Journal:  Trends Microbiol       Date:  2001-02       Impact factor: 17.079

Review 2.  Molecular properties of bacterial multidrug transporters.

Authors:  M Putman; H W van Veen; W N Konings
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

3.  Helicobacter pylori uptake and efflux: basis for intrinsic susceptibility to antibiotics in vitro.

Authors:  J E Bina; R A Alm; M Uria-Nickelsen; S R Thomas; T J Trust; R E Hancock
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

Review 4.  Proton-dependent multidrug efflux systems.

Authors:  I T Paulsen; M H Brown; R A Skurray
Journal:  Microbiol Rev       Date:  1996-12

5.  The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump.

Authors:  L Sánchez; W Pan; M Viñas; H Nikaido
Journal:  J Bacteriol       Date:  1997-11       Impact factor: 3.490

6.  Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those beta-lactam antibiotics containing lipophilic side chains.

Authors:  H Nikaido; M Basina; V Nguyen; E Y Rosenberg
Journal:  J Bacteriol       Date:  1998-09       Impact factor: 3.490

7.  Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

Authors:  K E Hagman; W Pan; B G Spratt; J T Balthazar; R C Judd; W M Shafer
Journal:  Microbiology       Date:  1995-03       Impact factor: 2.777

8.  Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa.

Authors:  X Z Li; H Nikaido; K Poole
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

9.  AcrAB multidrug efflux pump is associated with reduced levels of susceptibility to tigecycline (GAR-936) in Proteus mirabilis.

Authors:  Melissa A Visalli; Ellen Murphy; Steven J Projan; Patricia A Bradford
Journal:  Antimicrob Agents Chemother       Date:  2003-02       Impact factor: 5.191

10.  CmeABC functions as a multidrug efflux system in Campylobacter jejuni.

Authors:  Jun Lin; Linda Overbye Michel; Qijing Zhang
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191
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  26 in total

1.  Role of the HefC efflux pump in Helicobacter pylori cholesterol-dependent resistance to ceragenins and bile salts.

Authors:  Elizabeth A Trainor; Katherine E Horton; Paul B Savage; Traci L Testerman; David J McGee
Journal:  Infect Immun       Date:  2010-10-25       Impact factor: 3.441

2.  Resistance to clarithromycin and gastroenterologist's persistence roles in nomination for Helicobacter pylori as high priority pathogen by World Health Organization.

Authors:  Amin Talebi Bezmin Abadi
Journal:  World J Gastroenterol       Date:  2017-09-21       Impact factor: 5.742

3.  Pyridodiazepine amines are selective therapeutic agents for helicobacter pylori by suppressing growth through inhibition of glutamate racemase but are predicted to require continuous elevated levels in plasma to achieve clinical efficacy.

Authors:  Boudewijn L M de Jonge; Amy Kutschke; Joseph V Newman; Michael T Rooney; Wei Yang; Christer Cederberg
Journal:  Antimicrob Agents Chemother       Date:  2015-02-02       Impact factor: 5.191

Review 4.  Efflux-mediated drug resistance in bacteria: an update.

Authors:  Xian-Zhi Li; Hiroshi Nikaido
Journal:  Drugs       Date:  2009-08-20       Impact factor: 9.546

Review 5.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

6.  Mechanisms of Helicobacter pylori antibiotic resistance: An updated appraisal.

Authors:  Vincenzo De Francesco; Angelo Zullo; Cesare Hassan; Floriana Giorgio; Rosa Rosania; Enzo Ierardi
Journal:  World J Gastrointest Pathophysiol       Date:  2011-06-15

7.  Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori.

Authors:  Kathleen R Jones; Jeong-Heon Cha; D Scott Merrell
Journal:  Curr Drug ther       Date:  2008-09-01

8.  Gatifloxacin resistance and mutations in gyra after unsuccessful Helicobacter pylori eradication in Japan.

Authors:  Toshihiro Nishizawa; Hidekazu Suzuki; Kumiko Kurabayashi; Tatsuhiro Masaoka; Hiroe Muraoka; Mikiji Mori; Eisuke Iwasaki; Intetsu Kobayashi; Toshifumi Hibi
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

9.  Complexomics study of two Helicobacter pylori strains of two pathological origins: potential targets for vaccine development and new insight in bacteria metabolism.

Authors:  Cédric Bernarde; Philippe Lehours; Jean-Paul Lasserre; Michel Castroviejo; Marc Bonneu; Francis Mégraud; Armelle Ménard
Journal:  Mol Cell Proteomics       Date:  2010-07-07       Impact factor: 5.911

10.  Influence of efflux pump inhibitors on the multidrug resistance of Helicobacter pylori.

Authors:  Zhan Zhang; Zhi-Qiang Liu; Peng-Yuan Zheng; Fu-Ai Tang; Ping-Chang Yang
Journal:  World J Gastroenterol       Date:  2010-03-14       Impact factor: 5.742
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