Literature DB >> 15979798

pain1: a neuropathic pain QTL on mouse chromosome 15 in a C3HxC58 backcross.

Marshall Devor1, Amit Gilad, Michal Arbilly, Benjamin Yakir, Pnina Raber, Anne Pisanté, Ariel Darvasi.   

Abstract

We have produced a backcross (BC) population of 267 mice from the parental strains C3H/HeN and C58/J. The mice were phenotyped for neuropathic pain using the neuroma model. Subsequently all BC mice were genotyped in a region of chromosome 15 that has been previously suggested to contain a quantitative trait locus (QTL) for this trait. We have confirmed the linkage of the QTL, named pain1, to the central region of chromosome 15. Our finding provides the necessary robustness to justify efforts towards identification of the underlying gene.

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Year:  2005        PMID： 15979798     DOI： 10.1016/j.pain.2005.04.023

Source DB:  PubMed          Journal:  Pain        ISSN： 0304-3959            Impact factor:   6.961


  9 in total

1.  Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2.

Authors:  Jonathan Nissenbaum; Marshall Devor; Ze'ev Seltzer; Mathias Gebauer; Martin Michaelis; Michael Tal; Ruslan Dorfman; Merav Abitbul-Yarkoni; Yan Lu; Tina Elahipanah; Sonia delCanho; Anne Minert; Kaj Fried; Anna-Karin Persson; Hagai Shpigler; Erez Shabo; Benjamin Yakir; Anne Pisanté; Ariel Darvasi
Journal:  Genome Res       Date:  2010-08-05       Impact factor: 9.043

2.  Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test.

Authors:  E E Young; C D Bryant; S E Lee; X Peng; B Cook; H K Nair; K J Dreher; X Zhang; A A Palmer; J M Chung; J S Mogil; E J Chesler; W R Lariviere
Journal:  Genes Brain Behav       Date:  2016-07       Impact factor: 3.449

3.  Heritability of nociception IV: neuropathic pain assays are genetically distinct across methods of peripheral nerve injury.

Authors:  Erin E Young; Michael Costigan; Teri A Herbert; William R Lariviere
Journal:  Pain       Date:  2013-09-24       Impact factor: 6.961

Review 4.  Genetic and epigenetic mechanisms influencing acute to chronic postsurgical pain transitions in pediatrics: Preclinical to clinical evidence.

Authors:  Adam J Dourson; Adam Willits; Namrata G R Raut; Leena Kader; Erin Young; Michael P Jankowski; Vidya Chidambaran
Journal:  Can J Pain       Date:  2022-05-10

Review 5.  Progress in genetic studies of pain and analgesia.

Authors:  Michael L Lacroix-Fralish; Jeffrey S Mogil
Journal:  Annu Rev Pharmacol Toxicol       Date:  2009       Impact factor: 13.820

6.  Evolutionary conservation of metabolism explains howDrosophila nutrigenomics can help us understand human nutrigenomics.

Authors:  Douglas M Ruden; Xiangyi Lu
Journal:  Genes Nutr       Date:  2006-06       Impact factor: 4.423

7.  Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene.

Authors:  Jill M Recla; Raymond F Robledo; Daniel M Gatti; Carol J Bult; Gary A Churchill; Elissa J Chesler
Journal:  Mamm Genome       Date:  2014-04-05       Impact factor: 2.957

8.  Sources of individual variability: miRNAs that predispose to neuropathic pain identified using genome-wide sequencing.

Authors:  Kiran Kumar Bali; Michael Hackenberg; Avigail Lubin; Rohini Kuner; Marshall Devor
Journal:  Mol Pain       Date:  2014-03-19       Impact factor: 3.395

9.  Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury.

Authors:  Cecilia A Dominguez; Karl E Carlström; Xing-Mei Zhang; Faiez Al Nimer; Rickard P F Lindblom; Andre Ortlieb Guerreiro-Cacais; Fredrik Piehl
Journal:  Mol Pain       Date:  2014-12-10       Impact factor: 3.395
  9 in total

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