Literature DB >> 15979759

Regulation of thermogenesis by the central melanocortin system.

Wei Fan1, Adriana Voss-Andreae, Wei-Hua Cao, Shaun F Morrison.   

Abstract

Adaptive thermogenesis represents one of the important homeostatic mechanisms by which the body maintains appropriate levels of stored energy and its core temperature. Dysregulation of adaptive thermogenesis promotes obesity. The central melanocortin system, in particular the melanocortin 4 receptor (MC4R) signaling pathway, influences the regulation of every aspect of energy balance, including thermogenesis, and plays a critical role in energy homeostasis in both rodent and man. This review will outline our current understanding of adaptive thermogenesis, focusing on the role of the central melanocortin pathway in the regulation of thermogenesis.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15979759     DOI： 10.1016/j.peptides.2004.11.033

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  22 in total

1.  Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits.

Authors:  Yan Zhang; Ilan A Kerman; Amanda Laque; Phillip Nguyen; Miro Faouzi; Gwendolyn W Louis; Justin C Jones; Chris Rhodes; Heike Münzberg
Journal:  J Neurosci       Date:  2011-02-02       Impact factor: 6.167

Review 2.  Central nervous system regulation of brown adipose tissue.

Authors:  Shaun F Morrison; Christopher J Madden
Journal:  Compr Physiol       Date:  2014-10       Impact factor: 9.090

3.  Gsα deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsα mutations.

Authors:  Min Chen; Alta Berger; Ahmed Kablan; Jiandi Zhang; Oksana Gavrilova; Lee S Weinstein
Journal:  Endocrinology       Date:  2012-06-25       Impact factor: 4.736

4.  Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.

Authors:  Franck Chiappini; Lucas L Cunha; Jamie C Harris; Anthony N Hollenberg
Journal:  J Biol Chem       Date:  2011-01-05       Impact factor: 5.157

5.  Role of glucagon in the control of heat production in ducklings.

Authors:  A S H Squalli; M Slimani; Y Z Filali; M N Benchekroun; S Elantri; J L Rouanet; H Barre; T Fechtali
Journal:  J Neural Transm (Vienna)       Date:  2006-09-21       Impact factor: 3.575

6.  Fluoxetine induces lean phenotype in rat by increasing the brown/white adipose tissue ratio and UCP1 expression.

Authors:  A I da Silva; G R F Braz; A A Pedroza; L Nascimento; C M Freitas; D J S Ferreira; R Manhães de Castro; C J Lagranha
Journal:  J Bioenerg Biomembr       Date:  2015-07-01       Impact factor: 2.945

Review 7.  Integration of sensory information via central thermoregulatory leptin targets.

Authors:  Kavon Rezai-Zadeh; Heike Münzberg
Journal:  Physiol Behav       Date:  2013-02-28

8.  Naltrexone/Bupropion ER (Contrave): Newly Approved Treatment Option for Chronic Weight Management in Obese Adults.

Authors:  Matthew M Sherman; Sinziana Ungureanu; Jose A Rey
Journal:  P T       Date:  2016-03

Review 9.  The role of transcriptional regulators in central control of appetite and body weight.

Authors:  Roberto Coppari; Giorgio Ramadori; Joel K Elmquist
Journal:  Nat Clin Pract Endocrinol Metab       Date:  2009-03

10.  Mapping the structural requirements in the CB1 cannabinoid receptor transmembrane helix II for signal transduction.

Authors:  Ankur Kapur; Patrick Samaniego; Ganesh A Thakur; Alexandros Makriyannis; Mary E Abood
Journal:  J Pharmacol Exp Ther       Date:  2008-01-03       Impact factor: 4.030
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.