| Literature DB >> 15979499 |
Ian W Jones1, Susan Wonnacott.
Abstract
Immunochemical analyses of protein expression and localization rely on the specificity of primary immunoreagents. A recent report, using transgenic mice, casts doubt on the specificity of three antibodies commonly used to immunolocalize alpha7 nicotinic ACh receptors. These data highlight the conundrum facing histologists--how 'real' is the labelling they see?Entities:
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Year: 2005 PMID： 15979499 DOI： 10.1016/j.tins.2005.04.010
Source DB: PubMed Journal: Trends Neurosci ISSN： 0166-2236 Impact factor: 13.837