BACKGROUND: The Lundby Study is a prospective, longitudinal study on a total population consisting of 3563 subjects during 50 years. This study compares first incidence rates of depression and cumulative probabilities for developing a depression over the two time periods 1947-1972 and 1972-1997. METHOD: The Lundby Study started in 1947. Follow-ups were carried out in 1957 and in 1972. In 1997 the surviving subjects (N=1797) were interviewed by psychiatrists with a semi-structured interview. Best-estimate consensus diagnoses were used and ICD-10 and DSM-IV diagnoses were added. Further, 1030 subjects who had died during the last follow-up period 1972-1997 were investigated. RESULTS: Women had higher incidence rates than men in both periods. The average annual incidence rate was lower for women and tended to be lower for men 1972-1997 as compared with 1947-1972. The cumulative probability for developing a depression was 22.5% for men and 30.7% for women 1972-1997. In 1947-1972 the corresponding figures were 22.8% in men and 35.7% in women. LIMITATIONS: The recall period is of considerable length, probably introducing recall bias. The inter-rater reliability over 50 years is fairly acceptable concerning depression. CONCLUSION: Lower annual standardised incidence rates were seen in 1972-1997 compared with 1947-1972. These findings suggest that the trend of increasing rates of depression in the Lundby cohort has terminated. Incidence rates and cumulative probabilities to develop a depression were higher for women than for men, indicating that gender differences continue to play a role.
BACKGROUND: The Lundby Study is a prospective, longitudinal study on a total population consisting of 3563 subjects during 50 years. This study compares first incidence rates of depression and cumulative probabilities for developing a depression over the two time periods 1947-1972 and 1972-1997. METHOD: The Lundby Study started in 1947. Follow-ups were carried out in 1957 and in 1972. In 1997 the surviving subjects (N=1797) were interviewed by psychiatrists with a semi-structured interview. Best-estimate consensus diagnoses were used and ICD-10 and DSM-IV diagnoses were added. Further, 1030 subjects who had died during the last follow-up period 1972-1997 were investigated. RESULTS:Women had higher incidence rates than men in both periods. The average annual incidence rate was lower for women and tended to be lower for men 1972-1997 as compared with 1947-1972. The cumulative probability for developing a depression was 22.5% for men and 30.7% for women 1972-1997. In 1947-1972 the corresponding figures were 22.8% in men and 35.7% in women. LIMITATIONS: The recall period is of considerable length, probably introducing recall bias. The inter-rater reliability over 50 years is fairly acceptable concerning depression. CONCLUSION: Lower annual standardised incidence rates were seen in 1972-1997 compared with 1947-1972. These findings suggest that the trend of increasing rates of depression in the Lundby cohort has terminated. Incidence rates and cumulative probabilities to develop a depression were higher for women than for men, indicating that gender differences continue to play a role.
Authors: Eun Lee; Hyong Jin Cho; Richard Olmstead; Myron J Levin; Michael N Oxman; Michael R Irwin Journal: Sleep Date: 2013-11-01 Impact factor: 5.849
Authors: B F Grant; R B Goldstein; S P Chou; B Huang; F S Stinson; D A Dawson; T D Saha; S M Smith; A J Pulay; R P Pickering; W J Ruan; W M Compton Journal: Mol Psychiatry Date: 2008-04-22 Impact factor: 15.992
Authors: Carl Wikberg; Shabnam Nejati; Maria E H Larsson; Eva-Lisa Petersson; Jeanette Westman; Nashmil Ariai; Marie Kivi; Maria Eriksson; Robert Eggertsen; Dominique Hange; Amir Baigi; Cecilia Björkelund Journal: Prim Care Companion CNS Disord Date: 2015-06-25