Literature DB >> 15978337

Relatedness and DNA: are we taking it seriously enough?

John Buckleton1, Christopher M Triggs.   

Abstract

In forensic DNA testimony most DNA laboratories report the match probability for an unrelated person from some relevant population. These laboratories typically make available the match probability for relatives when requested. This practice has served well for many years. However, as the discrimination power of our multiplexes has increased the estimated match probabilities for both related and unrelated people have become markedly smaller. Associated with this general reduction in match probabilities have been the observations that the relative balance between the match probabilities of the many unrelated people and the few relatives of a suspect has changed. We suggest that we should now report routinely the match probability for a sibling whenever the suspect has a non-excluded sibling.

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Year:  2005        PMID: 15978337     DOI: 10.1016/j.forsciint.2004.07.020

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  4 in total

Review 1.  A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™.

Authors:  Peter Gill; Corina Benschop; John Buckleton; Øyvind Bleka; Duncan Taylor
Journal:  Genes (Basel)       Date:  2021-09-30       Impact factor: 4.096

2.  Probabilistic Genotyping of Single Cell Replicates from Mixtures Involving First-Degree Relatives Prevents the False Inclusions of Non-Donor Relatives.

Authors:  Kaitlin Huffman; Jack Ballantyne
Journal:  Genes (Basel)       Date:  2022-09-15       Impact factor: 4.141

3.  Automated genotyping of biobank samples by multiplex amplification of insertion/deletion polymorphisms.

Authors:  Lucy Mathot; Elin Falk-Sörqvist; Lotte Moens; Marie Allen; Tobias Sjöblom; Mats Nilsson
Journal:  PLoS One       Date:  2012-12-27       Impact factor: 3.240

4.  Must the random man be unrelated? A lingering misconception in forensic genetics.

Authors:  Emmanuel Milot; Simon Baechler; Frank Crispino
Journal:  Forensic Sci Int       Date:  2019-11-12       Impact factor: 2.395

  4 in total

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