Literature DB >> 15977943

Multimodal therapy of treatment resistant depression: a study and analysis.

Noreen Bannan1.   

Abstract

OBJECTIVE: To demonstrate through the use of a case study, the application of cognitive psychotherapy in the treatment of resistant depression.
METHOD: The case of a woman with an 18-month history of resistant depression associated with low self-esteem, guilt and shame, who failed to respond to three therapeutic trials of anti-depressants is described. A detailed description of a CBT intervention over 12 sessions is given. RESULT: Clear improvements on assessments of mood and hopelessness, along with overall improvements in social and occupational functioning were noted.
CONCLUSION: These improvements were attributed to a combination of CBT and pharmacotherapy, where pharmacotherapy alone failed to alleviate symptoms. A concise literature review revealed relatively few published trials of psychological treatments, and a lack of clear guidelines on pharmacological treatments. More research is needed to explore the efficacy of psychological therapies for treatment resistant depression.

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Year:  2005        PMID: 15977943     DOI: 10.2190/KAN6-M5HW-ADT2-P5AE

Source DB:  PubMed          Journal:  Int J Psychiatry Med        ISSN: 0091-2174            Impact factor:   1.210


  4 in total

Review 1.  Therapeutic options for treatment-resistant depression.

Authors:  Richard C Shelton; Olawale Osuntokun; Alexandra N Heinloth; Sara A Corya
Journal:  CNS Drugs       Date:  2010-02       Impact factor: 5.749

2.  Current nosology of treatment resistant depression: a controversy resistant to revision.

Authors:  Michele Fornaro; Patricia Giosuè
Journal:  Clin Pract Epidemiol Ment Health       Date:  2010-05-04

3.  Influence of comorbidity with depression on interdisciplinary therapy: outcomes in patients with chronic low back pain.

Authors:  Haili Wang; Carsten Ahrens; Winfried Rief; Marcus Schiltenwolf
Journal:  Arthritis Res Ther       Date:  2010-10-11       Impact factor: 5.156

4.  Approaches to understanding and addressing treatment-resistant depression: a scoping review.

Authors:  Emily Jenkins; Elliot M Goldner
Journal:  Depress Res Treat       Date:  2012-04-18
  4 in total

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