Literature DB >> 15977426

Technology evaluation: alicaforsen (Isis).

Andrew T Gewirtz1, Shanthi V Sitaraman.   

Abstract

Isis is developing alicaforsen, an RNase H-dependent antisense inhibitor of intercellular adhesion molecule-1, for the potential treatment of ulcerative colitis. The therapy is currently undergoing phase II clinical trials.

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Year:  2005        PMID: 15977426

Source DB:  PubMed          Journal:  Curr Opin Mol Ther        ISSN: 1464-8431


  1 in total

1.  Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.

Authors:  Moizza Mansoor; Alirio J Melendez
Journal:  Gene Regul Syst Bio       Date:  2008-09-22
  1 in total

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