| Literature DB >> 15977241 |
Youchun Wang1, Xiouhua Li, Aijing Song, Chuntao Zhang, Ying Chen, Changrong Chen, Yisheng Lin, Liping Shun, Luilan Li, Yanchun Liu, Jian Yang, Bowei Yang, Qiouping Tang, Tim J Harrison.
Abstract
A total of 145,293 serum samples were collected from volunteer blood donors in 13 provinces of China and tested for anti-HTLV antibody using an ELISA licensed in China. Thirty were positive for anti-HTLV by ELISA and 19 of those 30 samples were confirmed positive using a supplemental immunoblot assay. Anti-HTLV-I was detected only in samples from Fujian province (a Southern province) where the positivity rate was approximately 0.05%. The region encoding gp46 from 5 of the 19 antibody positive samples was amplified and sequenced. Sequence analysis indicated that these isolates belong to HTLV-I genotype A. These data suggest that HTLV-I is not endemic throughout China and the virus may be restricted to a particular region. (c) 2005 Wiley-Liss, Inc.Entities:
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Year: 2005 PMID： 15977241 DOI： 10.1002/jmv.20405
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327