| Literature DB >> 15975504 |
Abstract
(2S)-4-amino-2-hydroxybutyrate (AHBA) is a side chain that is important for the antibiotic activities of aminoglycosides. The elucidation of the biosynthetic pathway to AHBA, by Spencer et al. in this issue of Chemistry & Biology [1], reveals several surprises and will facilitate biosynthetic engineering of new improved aminoglycoside antibiotics.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15975504 DOI： 10.1016/j.chembiol.2005.06.002
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521