OBJECTIVE: Histamine, a derivative of histidine, decreases food intake by activation of histamine neurons. The aim of the present study was to clarify gender-related differences in food intake through the histidine-histamine neuron system. METHODS: Male, female, and ovariectomized rats were fed a histidine-enriched diet or a control diet with the cafeteria method. RESULTS: The suppressive effect of histidine on food intake was greater in female rats than in male rats, and the suppressive effect of histidine on food intake was less in ovariectomized rats than in female rats. CONCLUSION: Our results indicate that females are more sensitive than males to dietary histidine-induced anorexia.
OBJECTIVE:Histamine, a derivative of histidine, decreases food intake by activation of histamine neurons. The aim of the present study was to clarify gender-related differences in food intake through the histidine-histamine neuron system. METHODS: Male, female, and ovariectomized rats were fed a histidine-enriched diet or a control diet with the cafeteria method. RESULTS: The suppressive effect of histidine on food intake was greater in female rats than in male rats, and the suppressive effect of histidine on food intake was less in ovariectomized rats than in female rats. CONCLUSION: Our results indicate that females are more sensitive than males to dietary histidine-induced anorexia.
Authors: Asem H Ali; Lisa B Yanoff; Elizabeth A Stern; Abena Akomeah; Amber Courville; Merel Kozlosky; Sheila M Brady; Karim A Calis; James C Reynolds; Melissa K Crocker; Nir Barak; Jack A Yanovski Journal: Am J Clin Nutr Date: 2010-09-29 Impact factor: 7.045
Authors: Shahira F El-Menshawe; Adel Ahmed Ali; Abdelkhalk Ali Halawa; Ahmed Sg Srag El-Din Journal: Drug Des Devel Ther Date: 2017-11-28 Impact factor: 4.162
Authors: Mengbo Li; Benjamin L Parker; Evangeline Pearson; Benjamin Hunter; Jacob Cao; Yen Chin Koay; Oneka Guneratne; David E James; Jean Yang; Sean Lal; John F O'Sullivan Journal: Nat Commun Date: 2020-06-02 Impact factor: 14.919