Literature DB >> 15975018

Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development.

J D Miller1, D Masopust, E J Wherry, S Kaech, G Silvestri, R Ahmed.   

Abstract

Successful HIV vaccine strategies will likely require the induction of robust cellular immune responses, in addition to strong humoral responses. Unfortunately, there is no clear molecular definition of an effective HIV-specific CD8 T cell response. In this review, we discuss the differentiation of CD8 T cells in response to acute and chronic viral infections. We then apply concepts derived from these studies to predict the desirable characteristics of HIV-specific CD8 T cell memory.

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Year:  2005        PMID： 15975018     DOI： 10.2174/1568005054201544

Source DB:  PubMed          Journal:  Curr Drug Targets Infect Disord        ISSN： 1568-0053


  8 in total

1.  Killer T cells regulate antigen presentation for early expansion of memory, but not naive, CD8+ T cell.

Authors:  Gabrielle T Belz; Lei Zhang; Matthew D H Lay; Fiona Kupresanin; Miles P Davenport
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-30       Impact factor: 11.205

Review 2.  Nonhuman primate models of human immunology.

Authors:  Ilhem Messaoudi; Ryan Estep; Bridget Robinson; Scott W Wong
Journal:  Antioxid Redox Signal       Date:  2010-08-30       Impact factor: 8.401

3.  Improved genetic stability of recombinant yellow fever 17D virus expressing a lentiviral Gag gene fragment.

Authors:  Marlon G Veloso de Santana; Patrícia C C Neves; Juliana Ribeiro dos Santos; Noemia S Lima; Alexandre A C dos Santos; David I Watkins; Ricardo Galler; Myrna C Bonaldo
Journal:  Virology       Date:  2014-02-08       Impact factor: 3.616

4.  Transcriptional profiling of experimental CD8(+) lymphocyte depletion in rhesus macaques infected with simian immunodeficiency virus SIVmac239.

Authors:  Steven E Bosinger; Simon P Jochems; Kathryn A Folkner; Timothy L Hayes; Nichole R Klatt; Guido Silvestri
Journal:  J Virol       Date:  2012-10-24       Impact factor: 5.103

5.  CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.

Authors:  Nichole R Klatt; Emi Shudo; Alex M Ortiz; Jessica C Engram; Mirko Paiardini; Benton Lawson; Michael D Miller; James Else; Ivona Pandrea; Jacob D Estes; Cristian Apetrei; Joern E Schmitz; Ruy M Ribeiro; Alan S Perelson; Guido Silvestri
Journal:  PLoS Pathog       Date:  2010-01-29       Impact factor: 6.823

6.  HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127.

Authors:  Rebecca B Hasley; Changwan Hong; Wenqing Li; Travis Friesen; Yoriko Nakamura; Grace Y Kim; Jung-Hyun Park; Julie A Hixon; Scott Durum; Zonghui Hu; Michael C Sneller; Raphael Oguariri; Tomozumi Imamichi; H Clifford Lane; Marta Catalfamo
Journal:  AIDS       Date:  2013-07-31       Impact factor: 4.177

7.  Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection.

Authors:  Gaëlle Breton; Nicolas Chomont; Hiroshi Takata; Rémi Fromentin; Jeffrey Ahlers; Abdelali Filali-Mouhim; Catherine Riou; Mohamed-Rachid Boulassel; Jean-Pierre Routy; Bader Yassine-Diab; Rafick-Pierre Sékaly
Journal:  J Immunol       Date:  2013-08-05       Impact factor: 5.422

8.  Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control.

Authors:  Vikas Duhan; Vishal Khairnar; Sarah-Kim Friedrich; Fan Zhou; Asmae Gassa; Nadine Honke; Namir Shaabani; Nicole Gailus; Lacramioara Botezatu; Cyrus Khandanpour; Ulf Dittmer; Dieter Häussinger; Mike Recher; Cornelia Hardt; Philipp A Lang; Karl S Lang
Journal:  Sci Rep       Date:  2016-01-25       Impact factor: 4.379
  8 in total

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